Novel genomic methods for drug discovery and mechanism-based toxicological assessment.

Timothy W Gant; Shu-Dong Zhang; Emma L Taylor

Novel genomic methods for drug discovery and mechanism-based toxicological assessment.

Timothy W Gant, Shu-Dong Zhang, Emma L Taylor

Faculty Of Life & Health Sciences

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

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Abstract

Genomics encompasses a range of powerful technologies that can be applied at all levels of gene expression, from transcription to mRNA translation. Collectively, these technologies have great potential for improving drug discovery, both target and molecule recognition, and development. In this article we review the current and potential future status of established and novel genomic methods within drug discovery.

Original language	English
Pages (from-to)	72-80
Journal	Current Opinion in Drug Discovery and Development
Volume	12
Issue number	1
Publication status	Published (in print/issue) - Jan 2009

Keywords

Genomic methods
drug discovery
mechanism based toxicological assessment

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2009-CurrOpion-drug-toxicological-acceptedAuthor Accepted Manuscript, 494 KB

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title = "Novel genomic methods for drug discovery and mechanism-based toxicological assessment.",

abstract = "Genomics encompasses a range of powerful technologies that can be applied at all levels of gene expression, from transcription to mRNA translation. Collectively, these technologies have great potential for improving drug discovery, both target and molecule recognition, and development. In this article we review the current and potential future status of established and novel genomic methods within drug discovery.",

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AU - Taylor, Emma L

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AB - Genomics encompasses a range of powerful technologies that can be applied at all levels of gene expression, from transcription to mRNA translation. Collectively, these technologies have great potential for improving drug discovery, both target and molecule recognition, and development. In this article we review the current and potential future status of established and novel genomic methods within drug discovery.

KW - Genomic methods

KW - drug discovery

KW - mechanism based toxicological assessment

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EP - 80

JO - Current Opinion in Drug Discovery and Development

JF - Current Opinion in Drug Discovery and Development

IS - 1

ER -

Novel genomic methods for drug discovery and mechanism-based toxicological assessment.

Abstract

Keywords

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