Next generation transdermal drug delivery – An electrochemical approach to pH manipulationfor controlled release within smart patch technologies

A Anderson, J Davis

Research output: Contribution to journalArticle

Abstract

The development and characterization of a nanostructured conductive film capable of facilitating thecontrolled dissolution of enteric coatings is described. Electrochemical manipulation of the local pH within laser etched pores is shown to facilitate the controlled release of a model drug. Moreover, an innovate approach to the design and operation of microfiber pH probe is critically appraised and itsapplication to the prototype drug release system demonstrated.
LanguageEnglish
Pages919-922
JournalIFMBE Proceedings : World Congress on Medical Physics and Biomedical Engineering
Volume51
DOIs
Publication statusPublished - 7 Jun 2015

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Drug delivery
Conductive films
Pharmaceutical Preparations
Dissolution
Coatings
Lasers

Keywords

  • drug release
  • electrochemical
  • electrode
  • mems

Cite this

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title = "Next generation transdermal drug delivery – An electrochemical approach to pH manipulationfor controlled release within smart patch technologies",
abstract = "The development and characterization of a nanostructured conductive film capable of facilitating thecontrolled dissolution of enteric coatings is described. Electrochemical manipulation of the local pH within laser etched pores is shown to facilitate the controlled release of a model drug. Moreover, an innovate approach to the design and operation of microfiber pH probe is critically appraised and itsapplication to the prototype drug release system demonstrated.",
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AU - Davis, J

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AB - The development and characterization of a nanostructured conductive film capable of facilitating thecontrolled dissolution of enteric coatings is described. Electrochemical manipulation of the local pH within laser etched pores is shown to facilitate the controlled release of a model drug. Moreover, an innovate approach to the design and operation of microfiber pH probe is critically appraised and itsapplication to the prototype drug release system demonstrated.

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KW - electrochemical

KW - electrode

KW - mems

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