Nanostructuring carbon fibre probes for use in central venous catheters

M Li, J Phair, MF Cardosi, J Davis

    Research output: Contribution to journal › Article

    3 Citations (Scopus)

    Abstract

    A carbon fibre probe is described which utilises the oxidation of an endogenous biomarker to provide diagnostic information on the condition of intravascular access lines. The probe surface was modified through anodic oxidation to provide a high selectivity towards urate which was used as a redox probe through which the pH could be determined. A Nernstian response (−60 mV/pH) was obtained which was free from the interference of other redox species common to biofluids. The electroanalytical performance of the probe has been optimised and the applicability of the approach demonstrated through testing the responses in whole blood.
    LanguageEnglish
    Pages1-5
    JournalAnalytica Chimica Acta
    Volume812
    DOIs
    Publication statusPublished - 17 Feb 2014

    Fingerprint

    Central Venous Catheters
    Catheters
    Oxidation-Reduction
    probe
    Uric Acid
    Biomarkers
    oxidation
    Anodic oxidation
    biomarker
    Blood
    blood
    Oxidation
    carbon fiber
    Testing

    Cite this

    Li, M ; Phair, J ; Cardosi, MF ; Davis, J. / Nanostructuring carbon fibre probes for use in central venous catheters. In: Analytica Chimica Acta. 2014 ; Vol. 812. pp. 1-5.
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    abstract = "A carbon fibre probe is described which utilises the oxidation of an endogenous biomarker to provide diagnostic information on the condition of intravascular access lines. The probe surface was modified through anodic oxidation to provide a high selectivity towards urate which was used as a redox probe through which the pH could be determined. A Nernstian response (−60 mV/pH) was obtained which was free from the interference of other redox species common to biofluids. The electroanalytical performance of the probe has been optimised and the applicability of the approach demonstrated through testing the responses in whole blood.",
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    Li, M, Phair, J, Cardosi, MF & Davis, J 2014, 'Nanostructuring carbon fibre probes for use in central venous catheters', Analytica Chimica Acta, vol. 812, pp. 1-5. https://doi.org/10.1016/j.aca.2013.11.013

    Nanostructuring carbon fibre probes for use in central venous catheters. / Li, M; Phair, J; Cardosi, MF; Davis, J.

    In: Analytica Chimica Acta, Vol. 812, 17.02.2014, p. 1-5.

    Research output: Contribution to journal › Article

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    AU - Li, M

    AU - Phair, J

    AU - Cardosi, MF

    AU - Davis, J

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    N2 - A carbon fibre probe is described which utilises the oxidation of an endogenous biomarker to provide diagnostic information on the condition of intravascular access lines. The probe surface was modified through anodic oxidation to provide a high selectivity towards urate which was used as a redox probe through which the pH could be determined. A Nernstian response (−60 mV/pH) was obtained which was free from the interference of other redox species common to biofluids. The electroanalytical performance of the probe has been optimised and the applicability of the approach demonstrated through testing the responses in whole blood.

    AB - A carbon fibre probe is described which utilises the oxidation of an endogenous biomarker to provide diagnostic information on the condition of intravascular access lines. The probe surface was modified through anodic oxidation to provide a high selectivity towards urate which was used as a redox probe through which the pH could be determined. A Nernstian response (−60 mV/pH) was obtained which was free from the interference of other redox species common to biofluids. The electroanalytical performance of the probe has been optimised and the applicability of the approach demonstrated through testing the responses in whole blood.

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    Li M, Phair J, Cardosi MF, Davis J. Nanostructuring carbon fibre probes for use in central venous catheters. Analytica Chimica Acta. 2014 Feb 17;812:1-5. https://doi.org/10.1016/j.aca.2013.11.013

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