Nanostructuring carbon fibre probes for use in central venous catheters

M Li; J Phair; MF Cardosi; J Davis

doi:10.1016/j.aca.2013.11.013

Nanostructuring carbon fibre probes for use in central venous catheters

M Li, J Phair, MF Cardosi, J Davis

Research output: Contribution to journal › Article

3 Citations (Scopus)

Abstract

A carbon fibre probe is described which utilises the oxidation of an endogenous biomarker to provide diagnostic information on the condition of intravascular access lines. The probe surface was modified through anodic oxidation to provide a high selectivity towards urate which was used as a redox probe through which the pH could be determined. A Nernstian response (−60 mV/pH) was obtained which was free from the interference of other redox species common to biofluids. The electroanalytical performance of the probe has been optimised and the applicability of the approach demonstrated through testing the responses in whole blood.

Original language	English
Pages (from-to)	1-5
Number of pages	5
Journal	Analytica Chimica Acta
Volume	812
Early online date	27 Nov 2013
DOIs	https://doi.org/10.1016/j.aca.2013.11.013
Publication status	Published - 17 Feb 2014

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Keywords

Carbon fibre
Catheter
pH
Uric acid
Biofilm
Infection

Cite this

Li, M., Phair, J., Cardosi, MF., & Davis, J. (2014). Nanostructuring carbon fibre probes for use in central venous catheters. Analytica Chimica Acta, 812, 1-5. https://doi.org/10.1016/j.aca.2013.11.013

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AU - Cardosi, MF

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AB - A carbon fibre probe is described which utilises the oxidation of an endogenous biomarker to provide diagnostic information on the condition of intravascular access lines. The probe surface was modified through anodic oxidation to provide a high selectivity towards urate which was used as a redox probe through which the pH could be determined. A Nernstian response (−60 mV/pH) was obtained which was free from the interference of other redox species common to biofluids. The electroanalytical performance of the probe has been optimised and the applicability of the approach demonstrated through testing the responses in whole blood.

KW - Carbon fibre

KW - Catheter

KW - pH

KW - Uric acid

KW - Biofilm

KW - Infection

UR - https://pure.ulster.ac.uk/en/publications/nanostructuring-carbon-fibre-probes-for-use-in-central-venous-cat-3

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JO - Analytica Chimica Acta

JF - Analytica Chimica Acta

SN - 0003-2670

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