Nanoneuromedicine for management of neurodegenerative disorder

Nitin Dwivedi, Jigna Shah, Vijay Mishra, Murtaza M Tambuwala, Prashant Kesharwani

Research output: Contribution to journalArticle

19 Citations (Scopus)
54 Downloads (Pure)

Abstract

Conventional drug delivery systems are inadequate in providing essential cyto-architecture restoration and connection patterns because of restrictions posed by the restrictive blood-brain barrier. Nanotechnological approaches involve various nano-sized carrier systems and other devices, which stimulate the action of therapeutic agents on molecular level and revolutionized the treatment and diagnosis of neurodegenerative disorders with minimal side effects. Over the conventional approaches, nanotechnological approaches have various promising strategies to cross blood brain barrier and increase the bioavailability of therapeutics in brain. This review article emphasizes the current and future utility of nano drug delivery systems for the treatment of various neurodegenerative disorders.
Original languageEnglish
Pages (from-to)477-490
Number of pages13
JournalJournal of Drug Delivery Science and Technology
Volume49
Early online date21 Dec 2018
Publication statusE-pub ahead of print - 21 Dec 2018

Keywords

  • Parkinson disease
  • Neurodegenerative disorder
  • Nanotechnology
  • Alzheimers-Disease

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