Abstract
Conventional drug delivery systems are inadequate in providing essential cyto-architecture restoration and connection patterns because of restrictions posed by the restrictive blood-brain barrier. Nanotechnological approaches involve various nano-sized carrier systems and other devices, which stimulate the action of therapeutic agents on molecular level and revolutionized the treatment and diagnosis of neurodegenerative disorders with minimal side effects. Over the conventional approaches, nanotechnological approaches have various promising strategies to cross blood brain barrier and increase the bioavailability of therapeutics in brain. This review article emphasizes the current and future utility of nano drug delivery systems for the treatment of various neurodegenerative disorders.
| Original language | English |
|---|---|
| Pages (from-to) | 477-490 |
| Number of pages | 13 |
| Journal | Journal of Drug Delivery Science and Technology |
| Volume | 49 |
| Early online date | 21 Dec 2018 |
| Publication status | Published online - 21 Dec 2018 |
Keywords
- Parkinson disease
- Neurodegenerative disorder
- Nanotechnology
- Alzheimers-Disease
