TY - JOUR
T1 - Nanoarchitectures in Management of Fungal Diseases: An Overview
AU - Mishra, Vijay
AU - Singh, Manvendra
AU - Mishra, Yachana
AU - Charbe, Nitin
AU - Nayak, Pallavi
AU - Sudhakar, Kalvatala
AU - Aljabali, Alaa A. A.
AU - Shahcheraghi, Seyed H.
AU - Bakshi, Hamid
AU - Serrano-aroca, Ángel
AU - Tambuwala, Murtaza M.
PY - 2021/7/31
Y1 - 2021/7/31
N2 - Fungal infections, from mild itching to fatal infections, lead to chronic diseases and death. Antifungal agents have incorporated chemical compounds and natural products/phytoconstituents in the management of fungal diseases. In contrast to antibacterial research, novel antifungal drugs have progressed more swiftly because of their mild existence and negligible resistance of infections to antifungal bioactivities. Nanotechnology-based carriers have gained much attention due to their magnificent abilities. Nanoarchitectures have served as excellent carriers/drug delivery systems (DDS) for delivering antifungal drugs with improved antifungal activities, bioavailability, targeted action, and reduced cytotoxicity. This review outlines the different fungal diseases and their treatment strategies involving various nanocarrier-based techniques such as liposomes, transfersomes, ethosomes, transethosomes, niosomes, spanlastics, dendrimers, polymeric nanoparticles, polymer nanocomposites, metallic nanoparticles, carbon nanomaterials, and nanoemulsions, among other nanotechnological approaches.
AB - Fungal infections, from mild itching to fatal infections, lead to chronic diseases and death. Antifungal agents have incorporated chemical compounds and natural products/phytoconstituents in the management of fungal diseases. In contrast to antibacterial research, novel antifungal drugs have progressed more swiftly because of their mild existence and negligible resistance of infections to antifungal bioactivities. Nanotechnology-based carriers have gained much attention due to their magnificent abilities. Nanoarchitectures have served as excellent carriers/drug delivery systems (DDS) for delivering antifungal drugs with improved antifungal activities, bioavailability, targeted action, and reduced cytotoxicity. This review outlines the different fungal diseases and their treatment strategies involving various nanocarrier-based techniques such as liposomes, transfersomes, ethosomes, transethosomes, niosomes, spanlastics, dendrimers, polymeric nanoparticles, polymer nanocomposites, metallic nanoparticles, carbon nanomaterials, and nanoemulsions, among other nanotechnological approaches.
KW - antifungal drugs
KW - drug delivery
KW - fungal infection
KW - nanoarchitecture carriers
UR - https://www.mdpi.com/2076-3417/11/15/7119
U2 - 10.3390/app11157119
DO - 10.3390/app11157119
M3 - Review article
VL - 11
SP - 1
EP - 19
JO - Applied Sciences
JF - Applied Sciences
SN - 2076-3417
IS - 15
M1 - e7119
ER -
