Muscular adaptations and insulin-like growth factor-1 responses to resistance training are stretch-mediated.

Gerard Mc Mahon, Christopher L Morse, Adrian Burden, Keith Winwood, Gladys Leopoldine Onambele

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

INTRODUCTION: Modulation of muscle characteristics was attempted through altering muscle stretch during resistance training. We hypothesized that stretch would enhance muscle responses. METHODS: Participants trained for 8 weeks, loading the quadriceps in a shortened (SL, 0-50° knee flexion; n=10) or lengthened (LL, 40-90°; n=11) position, followed by 4 weeks of detraining. Controls (CON; n=10) were untrained. Quadriceps strength, vastus lateralis architecture, anatomical cross-sectional area (aCSA), and serum insulin-like growth factor-1 (IGF-1) were measured at weeks 0, 8, 10, and 12. RESULTS: Increases in fascicle length (29±4% vs. 14±4%), distal aCSA (53±12% vs. 18±8%), strength (26±6% vs. 7±3%), and IGF-1 (31±6% vs. 7±6%) were greater in LL compared with SL muscles (P<0.05). No changes occurred in CON. Detraining decrements in strength and aCSA were greater in SL than LL muscles (P<0.05). CONCLUSIONS: Enhanced muscle in vivo (and somewhat IGF-1) adaptations to resistance training are concurrent with muscle stretch, which warrants its inclusion within training.
LanguageEnglish
JournalMuscle Nerve
DOIs
Publication statusPublished - 1 Jan 2014

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Resistance Training
Somatomedins
Muscles
Quadriceps Muscle
Knee
Serum

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Mc Mahon, Gerard ; Morse, Christopher L ; Burden, Adrian ; Winwood, Keith ; Onambele, Gladys Leopoldine. / Muscular adaptations and insulin-like growth factor-1 responses to resistance training are stretch-mediated. 2014.
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abstract = "INTRODUCTION: Modulation of muscle characteristics was attempted through altering muscle stretch during resistance training. We hypothesized that stretch would enhance muscle responses. METHODS: Participants trained for 8 weeks, loading the quadriceps in a shortened (SL, 0-50° knee flexion; n=10) or lengthened (LL, 40-90°; n=11) position, followed by 4 weeks of detraining. Controls (CON; n=10) were untrained. Quadriceps strength, vastus lateralis architecture, anatomical cross-sectional area (aCSA), and serum insulin-like growth factor-1 (IGF-1) were measured at weeks 0, 8, 10, and 12. RESULTS: Increases in fascicle length (29±4{\%} vs. 14±4{\%}), distal aCSA (53±12{\%} vs. 18±8{\%}), strength (26±6{\%} vs. 7±3{\%}), and IGF-1 (31±6{\%} vs. 7±6{\%}) were greater in LL compared with SL muscles (P<0.05). No changes occurred in CON. Detraining decrements in strength and aCSA were greater in SL than LL muscles (P<0.05). CONCLUSIONS: Enhanced muscle in vivo (and somewhat IGF-1) adaptations to resistance training are concurrent with muscle stretch, which warrants its inclusion within training.",
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Muscular adaptations and insulin-like growth factor-1 responses to resistance training are stretch-mediated. / Mc Mahon, Gerard; Morse, Christopher L ; Burden, Adrian; Winwood, Keith; Onambele, Gladys Leopoldine.

01.01.2014.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Muscular adaptations and insulin-like growth factor-1 responses to resistance training are stretch-mediated.

AU - Mc Mahon, Gerard

AU - Morse, Christopher L

AU - Burden, Adrian

AU - Winwood, Keith

AU - Onambele, Gladys Leopoldine

PY - 2014/1/1

Y1 - 2014/1/1

N2 - INTRODUCTION: Modulation of muscle characteristics was attempted through altering muscle stretch during resistance training. We hypothesized that stretch would enhance muscle responses. METHODS: Participants trained for 8 weeks, loading the quadriceps in a shortened (SL, 0-50° knee flexion; n=10) or lengthened (LL, 40-90°; n=11) position, followed by 4 weeks of detraining. Controls (CON; n=10) were untrained. Quadriceps strength, vastus lateralis architecture, anatomical cross-sectional area (aCSA), and serum insulin-like growth factor-1 (IGF-1) were measured at weeks 0, 8, 10, and 12. RESULTS: Increases in fascicle length (29±4% vs. 14±4%), distal aCSA (53±12% vs. 18±8%), strength (26±6% vs. 7±3%), and IGF-1 (31±6% vs. 7±6%) were greater in LL compared with SL muscles (P<0.05). No changes occurred in CON. Detraining decrements in strength and aCSA were greater in SL than LL muscles (P<0.05). CONCLUSIONS: Enhanced muscle in vivo (and somewhat IGF-1) adaptations to resistance training are concurrent with muscle stretch, which warrants its inclusion within training.

AB - INTRODUCTION: Modulation of muscle characteristics was attempted through altering muscle stretch during resistance training. We hypothesized that stretch would enhance muscle responses. METHODS: Participants trained for 8 weeks, loading the quadriceps in a shortened (SL, 0-50° knee flexion; n=10) or lengthened (LL, 40-90°; n=11) position, followed by 4 weeks of detraining. Controls (CON; n=10) were untrained. Quadriceps strength, vastus lateralis architecture, anatomical cross-sectional area (aCSA), and serum insulin-like growth factor-1 (IGF-1) were measured at weeks 0, 8, 10, and 12. RESULTS: Increases in fascicle length (29±4% vs. 14±4%), distal aCSA (53±12% vs. 18±8%), strength (26±6% vs. 7±3%), and IGF-1 (31±6% vs. 7±6%) were greater in LL compared with SL muscles (P<0.05). No changes occurred in CON. Detraining decrements in strength and aCSA were greater in SL than LL muscles (P<0.05). CONCLUSIONS: Enhanced muscle in vivo (and somewhat IGF-1) adaptations to resistance training are concurrent with muscle stretch, which warrants its inclusion within training.

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