Modelling the generation of tinnitus in a silent environment

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Tinnitus is the phantom perception of a sound heard in or around the head in the absence of an identifiable source affecting 10-15% worldwide. The majority of tinnitus sufferers have some form of hearing loss. The multiple pathologies that generate and sustain tinnitus in a diverse tinnitus population make it challenging to establish a homogeneous cohort for experimental studies. People with no hearing loss or previous experience of tinnitus also begin to perceive phantom sounds when situated in a sound proof room for five minutes or less. This is consistently observed across multiple studies. Studies that induced tinnitus through acoustic deprivation in healthy subjects provide a more controlled environment to observe tinnitus. Although experimental work shows what is happening it does not explain how the tinnitus related activity is generated. Computational modelling of tinnitus following hearing loss has shown that underlying mechanisms, such as adaptive gain, can generate hyperactivity in the regions of hearing loss. These models do not account for the generation of tinnitus in people with no hearing loss. In this work we model the development of tinnitus related activity in cases of no hearing loss and induced acoustic deprivation. The tinnitus related activity disappears once the model is returned to normal ambient noise.
LanguageEnglish
Title of host publicationUnknown Host Publication
Number of pages6
DOIs
Publication statusE-pub ahead of print - 3 Nov 2016
Event2016 International Joint Conference on Neural Networks (IJCNN), -
Duration: 3 Nov 2016 → …

Conference

Conference2016 International Joint Conference on Neural Networks (IJCNN),
Period3/11/16 → …

Fingerprint

Tinnitus
Hearing Loss
Acoustics
Controlled Environment
Noise
Healthy Volunteers
Cohort Studies
Head

Keywords

  • Tinnitus modelling

Cite this

@inproceedings{7cca7bb028aa4d1e92bf2f6cef465bde,
title = "Modelling the generation of tinnitus in a silent environment",
abstract = "Tinnitus is the phantom perception of a sound heard in or around the head in the absence of an identifiable source affecting 10-15{\%} worldwide. The majority of tinnitus sufferers have some form of hearing loss. The multiple pathologies that generate and sustain tinnitus in a diverse tinnitus population make it challenging to establish a homogeneous cohort for experimental studies. People with no hearing loss or previous experience of tinnitus also begin to perceive phantom sounds when situated in a sound proof room for five minutes or less. This is consistently observed across multiple studies. Studies that induced tinnitus through acoustic deprivation in healthy subjects provide a more controlled environment to observe tinnitus. Although experimental work shows what is happening it does not explain how the tinnitus related activity is generated. Computational modelling of tinnitus following hearing loss has shown that underlying mechanisms, such as adaptive gain, can generate hyperactivity in the regions of hearing loss. These models do not account for the generation of tinnitus in people with no hearing loss. In this work we model the development of tinnitus related activity in cases of no hearing loss and induced acoustic deprivation. The tinnitus related activity disappears once the model is returned to normal ambient noise.",
keywords = "Tinnitus modelling",
author = "Richard Gault and T.Martin McGinnity and Sonya Coleman",
year = "2016",
month = "11",
day = "3",
doi = "10.1109/IJCNN.2016.7727863",
language = "English",
isbn = "978-1-5090-0620-5",
booktitle = "Unknown Host Publication",

}

Gault, R, McGinnity, TM & Coleman, S 2016, Modelling the generation of tinnitus in a silent environment. in Unknown Host Publication. 2016 International Joint Conference on Neural Networks (IJCNN), 3/11/16. https://doi.org/10.1109/IJCNN.2016.7727863

Modelling the generation of tinnitus in a silent environment. / Gault, Richard; McGinnity, T.Martin; Coleman, Sonya.

Unknown Host Publication. 2016.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

TY - GEN

T1 - Modelling the generation of tinnitus in a silent environment

AU - Gault, Richard

AU - McGinnity, T.Martin

AU - Coleman, Sonya

PY - 2016/11/3

Y1 - 2016/11/3

N2 - Tinnitus is the phantom perception of a sound heard in or around the head in the absence of an identifiable source affecting 10-15% worldwide. The majority of tinnitus sufferers have some form of hearing loss. The multiple pathologies that generate and sustain tinnitus in a diverse tinnitus population make it challenging to establish a homogeneous cohort for experimental studies. People with no hearing loss or previous experience of tinnitus also begin to perceive phantom sounds when situated in a sound proof room for five minutes or less. This is consistently observed across multiple studies. Studies that induced tinnitus through acoustic deprivation in healthy subjects provide a more controlled environment to observe tinnitus. Although experimental work shows what is happening it does not explain how the tinnitus related activity is generated. Computational modelling of tinnitus following hearing loss has shown that underlying mechanisms, such as adaptive gain, can generate hyperactivity in the regions of hearing loss. These models do not account for the generation of tinnitus in people with no hearing loss. In this work we model the development of tinnitus related activity in cases of no hearing loss and induced acoustic deprivation. The tinnitus related activity disappears once the model is returned to normal ambient noise.

AB - Tinnitus is the phantom perception of a sound heard in or around the head in the absence of an identifiable source affecting 10-15% worldwide. The majority of tinnitus sufferers have some form of hearing loss. The multiple pathologies that generate and sustain tinnitus in a diverse tinnitus population make it challenging to establish a homogeneous cohort for experimental studies. People with no hearing loss or previous experience of tinnitus also begin to perceive phantom sounds when situated in a sound proof room for five minutes or less. This is consistently observed across multiple studies. Studies that induced tinnitus through acoustic deprivation in healthy subjects provide a more controlled environment to observe tinnitus. Although experimental work shows what is happening it does not explain how the tinnitus related activity is generated. Computational modelling of tinnitus following hearing loss has shown that underlying mechanisms, such as adaptive gain, can generate hyperactivity in the regions of hearing loss. These models do not account for the generation of tinnitus in people with no hearing loss. In this work we model the development of tinnitus related activity in cases of no hearing loss and induced acoustic deprivation. The tinnitus related activity disappears once the model is returned to normal ambient noise.

KW - Tinnitus modelling

U2 - 10.1109/IJCNN.2016.7727863

DO - 10.1109/IJCNN.2016.7727863

M3 - Conference contribution

SN - 978-1-5090-0620-5

BT - Unknown Host Publication

ER -