Microneedle Array Sensors Based on Carbon Nano Particle Composites: Interfacial Chemistry and Electroanalytical Properties

Research output: Contribution to journalArticle

Abstract

Conductive microneedle patches consisting of carbon nanoparticles embedded in a polystyrene matrix have been prepared using micro-moulding techniques. The interfacial properties of the structures before and after electrochemical etching have been characterised using X-ray photoelectron spectroscopy and contact angle. Anodisation of the needles leads to a significant increase in oxygen functionality and is shown to dramatically improve the electroanalytical capabilities of the microneedle array. The detection of uric acid in horse blood was used as a model system through which to assess the performance of the system. The composite approach is shown to lead to viable carbon-based sensors and can offer a rapid prototype option for the development of tailored microneedle systems.

LanguageEnglish
Pages10705-10714
Number of pages10
JournalJournal of Materials Science
Volume54
Issue number15
Early online date30 Apr 2019
DOIs
Publication statusPublished - 15 Aug 2019

Fingerprint

Sensor arrays
Surface chemistry
Carbon
Electrochemical etching
Polystyrenes
Composite materials
Uric Acid
Molding
Needles
Contact angle
Blood
X ray photoelectron spectroscopy
Oxygen
Nanoparticles
Acids
Sensors

Keywords

  • Composite
  • Microneedle
  • Electrode
  • Sensor
  • Urate
  • Transdermal

Cite this

@article{884531defb7f45d7b72880a04404a55f,
title = "Microneedle Array Sensors Based on Carbon Nano Particle Composites: Interfacial Chemistry and Electroanalytical Properties",
abstract = "Conductive microneedle patches consisting of carbon nanoparticles embedded in a polystyrene matrix have been prepared using micro-moulding techniques. The interfacial properties of the structures before and after electrochemical etching have been characterised using X-ray photoelectron spectroscopy and contact angle. Anodisation of the needles leads to a significant increase in oxygen functionality and is shown to dramatically improve the electroanalytical capabilities of the microneedle array. The detection of uric acid in horse blood was used as a model system through which to assess the performance of the system. The composite approach is shown to lead to viable carbon-based sensors and can offer a rapid prototype option for the development of tailored microneedle systems.",
keywords = "Composite, Microneedle, Electrode, Sensor, Urate, Transdermal",
author = "Catherine Hegarty and Stephen McKillop and {Mc Glynn}, Ruairi and Robert Smith and Ashish Mathur and J Davis",
year = "2019",
month = "8",
day = "15",
doi = "10.1007/s10853-019-03642-1",
language = "English",
volume = "54",
pages = "10705--10714",
journal = "Journal of Materials Science",
issn = "0022-2461",
number = "15",

}

TY - JOUR

T1 - Microneedle Array Sensors Based on Carbon Nano Particle Composites: Interfacial Chemistry and Electroanalytical Properties

AU - Hegarty, Catherine

AU - McKillop, Stephen

AU - Mc Glynn, Ruairi

AU - Smith, Robert

AU - Mathur, Ashish

AU - Davis, J

PY - 2019/8/15

Y1 - 2019/8/15

N2 - Conductive microneedle patches consisting of carbon nanoparticles embedded in a polystyrene matrix have been prepared using micro-moulding techniques. The interfacial properties of the structures before and after electrochemical etching have been characterised using X-ray photoelectron spectroscopy and contact angle. Anodisation of the needles leads to a significant increase in oxygen functionality and is shown to dramatically improve the electroanalytical capabilities of the microneedle array. The detection of uric acid in horse blood was used as a model system through which to assess the performance of the system. The composite approach is shown to lead to viable carbon-based sensors and can offer a rapid prototype option for the development of tailored microneedle systems.

AB - Conductive microneedle patches consisting of carbon nanoparticles embedded in a polystyrene matrix have been prepared using micro-moulding techniques. The interfacial properties of the structures before and after electrochemical etching have been characterised using X-ray photoelectron spectroscopy and contact angle. Anodisation of the needles leads to a significant increase in oxygen functionality and is shown to dramatically improve the electroanalytical capabilities of the microneedle array. The detection of uric acid in horse blood was used as a model system through which to assess the performance of the system. The composite approach is shown to lead to viable carbon-based sensors and can offer a rapid prototype option for the development of tailored microneedle systems.

KW - Composite

KW - Microneedle

KW - Electrode

KW - Sensor

KW - Urate

KW - Transdermal

UR - http://www.scopus.com/inward/record.url?scp=85065237747&partnerID=8YFLogxK

U2 - 10.1007/s10853-019-03642-1

DO - 10.1007/s10853-019-03642-1

M3 - Article

VL - 54

SP - 10705

EP - 10714

JO - Journal of Materials Science

T2 - Journal of Materials Science

JF - Journal of Materials Science

SN - 0022-2461

IS - 15

ER -