Microneedle Array Sensors Based on Carbon Nano Particle Composites: Interfacial Chemistry and Electroanalytical Properties

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Abstract

Conductive microneedle patches consisting of carbon nanoparticles embedded in a polystyrene matrix have been prepared using micro-moulding techniques. The interfacial properties of the structures before and after electrochemical etching have been characterised using X-ray photoelectron spectroscopy and contact angle. Anodisation of the needles leads to a significant increase in oxygen functionality and is shown to dramatically improve the electroanalytical capabilities of the microneedle array. The detection of uric acid in horse blood was used as a model system through which to assess the performance of the system. The composite approach is shown to lead to viable carbon-based sensors and can offer a rapid prototype option for the development of tailored microneedle systems.

Original languageEnglish
Pages (from-to)10705-10714
Number of pages10
JournalJournal of Materials Science
Volume54
Issue number15
Early online date30 Apr 2019
DOIs
Publication statusPublished - 15 Aug 2019

Keywords

  • Composite
  • Microneedle
  • Electrode
  • Sensor
  • Urate
  • Transdermal

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