Microbubble-sonosensitiser conjugates as therapeutics in sonodynamic therapy

Nikolitsa Nomikou, Colin Fowley, Niall M. Byrne, Bridgeen McCaughan, AP MCHALE, John F. Callan

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

A Rose Bengal sonosensitiser has been covalently attached to a lipid microbubble and the resulting conjugate shown to produce higher levels of singlet oxygen, enhanced cytotoxicity in a cancer cell line and a greater reduction in tumour growth than the sonosensitiser alone.
LanguageEnglish
Pages8332-8334
JournalChemical Communications
Volume48
Issue number67
DOIs
Publication statusPublished - 2012

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Rose Bengal
Singlet Oxygen
Cytotoxicity
Tumors
Cells
Lipids

Cite this

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Microbubble-sonosensitiser conjugates as therapeutics in sonodynamic therapy. / Nomikou, Nikolitsa; Fowley, Colin; Byrne, Niall M.; McCaughan, Bridgeen; MCHALE, AP; Callan, John F.

In: Chemical Communications, Vol. 48, No. 67, 2012, p. 8332-8334.

Research output: Contribution to journalArticle

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AU - Nomikou, Nikolitsa

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AU - MCHALE, AP

AU - Callan, John F.

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