Microbubble-sonosensitiser conjugates as therapeutics in sonodynamic therapy

Nikolitsa Nomikou, Colin Fowley, Niall M. Byrne, Bridgeen McCaughan, AP MCHALE, John F. Callan

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

A Rose Bengal sonosensitiser has been covalently attached to a lipid microbubble and the resulting conjugate shown to produce higher levels of singlet oxygen, enhanced cytotoxicity in a cancer cell line and a greater reduction in tumour growth than the sonosensitiser alone.
Original languageEnglish
Pages (from-to)8332-8334
JournalChemical Communications
Volume48
Issue number67
DOIs
Publication statusPublished - 2012

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