Methyl mercury exposure and neurodevelopmental outcomes in the Seychelles Child Development Study Main cohort at age 22 and 24years

Edwin van Wijngaarden, Sally W. Thurston, Gary J. Myers, Donald Harrington, Deborah A. Cory-Slechta, JJ Strain, Gene E. Watson, Grazyna Zareba, Tanzy Love, Juliette Henderson, Conrad F. Shamlaye, Philip W. Davidson

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Abstract

All fish contain methyl mercury (MeHg), a known neurotoxicant at adequate dosage. There is still substantial scientific uncertainty about the consequences, if any, of mothers consuming fish with naturally-acquired levels of MeHg contamination. In 1989-1990, we recruited the Main Cohort of the Seychelles Child Development Study to assess the potential developmental effects of prenatal MeHg exposure. We report here on associations with neurodevelopmental outcomes obtained at 22 and 24years of age.
Original languageEnglish
Pages (from-to)35-42
Number of pages7
JournalNeurotoxicology and Teratology
Volume59
Early online date28 Oct 2016
DOIs
Publication statusPublished - 28 Feb 2017

Keywords

  • Methyl mercury
  • prenatal exposure
  • postnatal exposure
  • child development

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    van Wijngaarden, E., Thurston, S. W., Myers, G. J., Harrington, D., Cory-Slechta, D. A., Strain, JJ., Watson, G. E., Zareba, G., Love, T., Henderson, J., Shamlaye, C. F., & Davidson, P. W. (2017). Methyl mercury exposure and neurodevelopmental outcomes in the Seychelles Child Development Study Main cohort at age 22 and 24years. Neurotoxicology and Teratology, 59, 35-42. https://doi.org/10.1016/j.ntt.2016.10.011