Methodological issues in assessing change in dietary intake and appetite following gastric bypass surgery: A systematic review

Tamsyn L. Redpath, M. Barbara E. Livingstone, Aoibheann A. Dunne, Adele Boyd, Carel W. Roux, Alan C. Spector, Ruth K. Price

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)
82 Downloads (Pure)


Summary: Gastric bypass surgery is an effective long‐term treatment for individuals with severe obesity. Changes in appetite, dietary intake, and food preferences have all been postulated to contribute to postoperative body weight regulation, however, findings are inconsistent. The aim of this systematic review was to evaluate the current literature on changes in dietary intake and appetite following gastric bypass surgery, in the context of the methodology used and the analysis, interpretation, and presentation of results. Four databases were systematically searched with terms related to “gastric bypass surgery,” “appetite,” and “dietary intake,” and 49 papers (n = 2384 patients after gastric bypass) were eligible for inclusion. The evidence indicated that only a reduction in overall energy intake and an increase in postprandial satiety are maintained beyond 6‐month post‐surgery, whereas relative macronutrient intake and premeal hunger remain unchanged. However, available data were limited by inconsistencies in the methods, analysis, presentation, and interpretation of results. In particular, there was a reliance on data collected by subjective methods with minimal acknowledgment of the limitations, such as misreporting of food intake. There is a need for further work employing objective measurement of appetite and dietary intake following gastric bypass surgery to determine how these mechanisms may contribute to weight regulation in the longer term.
Original languageEnglish
Article numbere13202
Pages (from-to)1-19
Number of pages19
JournalObesity Reviews
Issue number6
Early online date1 Feb 2021
Publication statusPublished (in print/issue) - 1 Jun 2021

Bibliographical note

Funding Information:
US‐Ireland Research and Development Partnership program, Grant/Award Number: R01‐DK106112‐01A1; National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health, Grant/Award Number: R01DK106112; Health Research Board of the Republic of Ireland, Grant/Award Number: USIRL‐2006; Medical Research Council, UK, Grant/Award Number: MC_PC_16017; Health and Social Care R&D Division of Northern Ireland, Grant/Award Number: STL/5062/14

Publisher Copyright:
© 2021 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of World Obesity Federation

Copyright 2021 Elsevier B.V., All rights reserved.


  • Public Health, Environmental and Occupational Health
  • Endocrinology, Diabetes and Metabolism
  • dietary intake
  • appetite
  • gastric bypass
  • methodology


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