Method for Angiographically Guided Fine-Needle Diathermy in the Treatment of Corneal Neovascularization

Vito Romano, Bernhard Steger, Matthias Brunner, Sajjad Ahmad, Colin Willoughby, Stephen B. Kaye

    Research output: Contribution to journalArticle

    10 Citations (Scopus)

    Abstract

    PURPOSE:To describe a method to assess corneal neovascular (CoNV) complexes and identify feeder vessels for selective arterial fine-needle diathermy (FND).METHODS:In patients with CoNV, color photography and corneal indocyanine green angiography (ICGA) and fluorescein angiography are performed. After injection of indocyanine green and sodium fluorescein dye, videography and single-frame images of the region of interest are recorded. Videography is used to measure the time to leakage to assess vessel maturity to guide medical treatment and to discern afferent from efferent vessels. Single-frame images are then selected to locate the number of afferent vessels for surgery, which are selectively cut with a 25-gauge marked needle for the application of FND.RESULTS:Angiography using fluorescein and indocyanine green allows the characterization of CoNV based on assessment of both morphologic (ICGA) and functional (fluorescein angiography) parameters. The time to leakage of fluorescein dye provides important functional information on vessel maturity and helps discern whether medical treatment should be followed before surgical. ICGA allows the identification and delineation of afferent feeder vessels even in the presence of corneal opacities affecting biomicroscopic visibility. Colocalizing the afferent vessel to a visible venous landmark or branch is helpful for placement of the incision and application of FND. Using the described approach, angiographically identified feeder vessels can be selectively treated by FND with minimal thermal energy applied to the corneoscleral limbus.CONCLUSIONS:The described method for angiographically guided assessment of CoNV is a useful approach for guiding the medical and surgical treatment of CoNV.
    LanguageEnglish
    Pages1029-1032
    JournalCORNEA
    Volume35
    Issue number7
    DOIs
    Publication statusAccepted/In press - 9 Mar 2016

    Fingerprint

    Corneal Neovascularization
    Diathermy
    Indocyanine Green
    Needles
    Fluorescein Angiography
    Angiography
    Fluorescein
    Coloring Agents
    Corneal Opacity
    Therapeutics
    Photography
    Color
    Hot Temperature
    Injections

    Keywords

    • corneal neovascularization
    • fine-needle diathermy
    • angiography
    • anterior segment examination

    Cite this

    Romano, Vito ; Steger, Bernhard ; Brunner, Matthias ; Ahmad, Sajjad ; Willoughby, Colin ; Kaye, Stephen B. / Method for Angiographically Guided Fine-Needle Diathermy in the Treatment of Corneal Neovascularization. In: CORNEA. 2016 ; Vol. 35, No. 7. pp. 1029-1032.
    @article{5f6b5be65b8d4c98acb1b6da89450ce4,
    title = "Method for Angiographically Guided Fine-Needle Diathermy in the Treatment of Corneal Neovascularization",
    abstract = "PURPOSE:To describe a method to assess corneal neovascular (CoNV) complexes and identify feeder vessels for selective arterial fine-needle diathermy (FND).METHODS:In patients with CoNV, color photography and corneal indocyanine green angiography (ICGA) and fluorescein angiography are performed. After injection of indocyanine green and sodium fluorescein dye, videography and single-frame images of the region of interest are recorded. Videography is used to measure the time to leakage to assess vessel maturity to guide medical treatment and to discern afferent from efferent vessels. Single-frame images are then selected to locate the number of afferent vessels for surgery, which are selectively cut with a 25-gauge marked needle for the application of FND.RESULTS:Angiography using fluorescein and indocyanine green allows the characterization of CoNV based on assessment of both morphologic (ICGA) and functional (fluorescein angiography) parameters. The time to leakage of fluorescein dye provides important functional information on vessel maturity and helps discern whether medical treatment should be followed before surgical. ICGA allows the identification and delineation of afferent feeder vessels even in the presence of corneal opacities affecting biomicroscopic visibility. Colocalizing the afferent vessel to a visible venous landmark or branch is helpful for placement of the incision and application of FND. Using the described approach, angiographically identified feeder vessels can be selectively treated by FND with minimal thermal energy applied to the corneoscleral limbus.CONCLUSIONS:The described method for angiographically guided assessment of CoNV is a useful approach for guiding the medical and surgical treatment of CoNV.",
    keywords = "corneal neovascularization, fine-needle diathermy, angiography, anterior segment examination",
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    Method for Angiographically Guided Fine-Needle Diathermy in the Treatment of Corneal Neovascularization. / Romano, Vito; Steger, Bernhard; Brunner, Matthias; Ahmad, Sajjad; Willoughby, Colin; Kaye, Stephen B.

    In: CORNEA, Vol. 35, No. 7, 09.03.2016, p. 1029-1032.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Method for Angiographically Guided Fine-Needle Diathermy in the Treatment of Corneal Neovascularization

    AU - Romano, Vito

    AU - Steger, Bernhard

    AU - Brunner, Matthias

    AU - Ahmad, Sajjad

    AU - Willoughby, Colin

    AU - Kaye, Stephen B.

    PY - 2016/3/9

    Y1 - 2016/3/9

    N2 - PURPOSE:To describe a method to assess corneal neovascular (CoNV) complexes and identify feeder vessels for selective arterial fine-needle diathermy (FND).METHODS:In patients with CoNV, color photography and corneal indocyanine green angiography (ICGA) and fluorescein angiography are performed. After injection of indocyanine green and sodium fluorescein dye, videography and single-frame images of the region of interest are recorded. Videography is used to measure the time to leakage to assess vessel maturity to guide medical treatment and to discern afferent from efferent vessels. Single-frame images are then selected to locate the number of afferent vessels for surgery, which are selectively cut with a 25-gauge marked needle for the application of FND.RESULTS:Angiography using fluorescein and indocyanine green allows the characterization of CoNV based on assessment of both morphologic (ICGA) and functional (fluorescein angiography) parameters. The time to leakage of fluorescein dye provides important functional information on vessel maturity and helps discern whether medical treatment should be followed before surgical. ICGA allows the identification and delineation of afferent feeder vessels even in the presence of corneal opacities affecting biomicroscopic visibility. Colocalizing the afferent vessel to a visible venous landmark or branch is helpful for placement of the incision and application of FND. Using the described approach, angiographically identified feeder vessels can be selectively treated by FND with minimal thermal energy applied to the corneoscleral limbus.CONCLUSIONS:The described method for angiographically guided assessment of CoNV is a useful approach for guiding the medical and surgical treatment of CoNV.

    AB - PURPOSE:To describe a method to assess corneal neovascular (CoNV) complexes and identify feeder vessels for selective arterial fine-needle diathermy (FND).METHODS:In patients with CoNV, color photography and corneal indocyanine green angiography (ICGA) and fluorescein angiography are performed. After injection of indocyanine green and sodium fluorescein dye, videography and single-frame images of the region of interest are recorded. Videography is used to measure the time to leakage to assess vessel maturity to guide medical treatment and to discern afferent from efferent vessels. Single-frame images are then selected to locate the number of afferent vessels for surgery, which are selectively cut with a 25-gauge marked needle for the application of FND.RESULTS:Angiography using fluorescein and indocyanine green allows the characterization of CoNV based on assessment of both morphologic (ICGA) and functional (fluorescein angiography) parameters. The time to leakage of fluorescein dye provides important functional information on vessel maturity and helps discern whether medical treatment should be followed before surgical. ICGA allows the identification and delineation of afferent feeder vessels even in the presence of corneal opacities affecting biomicroscopic visibility. Colocalizing the afferent vessel to a visible venous landmark or branch is helpful for placement of the incision and application of FND. Using the described approach, angiographically identified feeder vessels can be selectively treated by FND with minimal thermal energy applied to the corneoscleral limbus.CONCLUSIONS:The described method for angiographically guided assessment of CoNV is a useful approach for guiding the medical and surgical treatment of CoNV.

    KW - corneal neovascularization

    KW - fine-needle diathermy

    KW - angiography

    KW - anterior segment examination

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    DO - 10.1097/ICO.0000000000000865

    M3 - Article

    VL - 35

    SP - 1029

    EP - 1032

    JO - CORNEA

    T2 - CORNEA

    JF - CORNEA

    SN - 0277-3740

    IS - 7

    ER -