Medikamentöse Therapie der Adipositas – Konkurrenz zur bariatrischen Chirurgie oder sinnvolle Ergänzung?

Translated title of the contribution: Pharmacotherapy of obesity—Competition to bariatric surgery or a meaningful supplement?

Tina Mazaheri, Saleem Ansari, Madhavi Nallagonda, Lars Kollmann, Felix Nickel, Florian Seyfried, Alexander Dimitri Miras

Research output: Contribution to journalReview articlepeer-review

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Abstract

Obesity is a complex chronic disease and requires a long-term multimodal approach. The current treatment algorithm for treatment of obesity mainly consists of a stepwise approach, which starts with a lifestyle intervention followed by or combined with medication treatment, whereas bariatric surgery is often reserved for the last option. This article provides an overview of the currently available conservative medicinal treatment regimens and the currently approved medications as well as medications currently undergoing approval studies with respect to the efficacy and possible side effects. Special attention is paid to the importance of combination treatment of pharmacotherapy and surgery in the sense of a multimodal treatment. The data so far show that using a multimodal approach an improvement in the long-term weight loss and metabolic benefits can be achieved for the patients. [Abstract copyright: © 2023. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.]
Translated title of the contributionPharmacotherapy of obesity—Competition to bariatric surgery or a meaningful supplement?
Original languageGerman
Pages (from-to)497-505
Number of pages9
JournalDie Chirurgie
Volume94
Issue number6
Early online date14 Mar 2023
DOIs
Publication statusPublished (in print/issue) - 14 Mar 2023

Bibliographical note

Publisher Copyright:
© 2023, The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.

Keywords

  • Side effects
  • Long-term weight loss
  • Efficacy
  • Treatment algorithm
  • Combined treatment
  • Life Style
  • Anti-Obesity Agents/therapeutic use
  • Humans
  • Combined Modality Therapy
  • Bariatric Surgery/adverse effects
  • Obesity/drug therapy

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