Measuring spinal mobility using an inertial measurement unit system: a validation study in axial spondyloarthritis

I. Concepción Aranda-Valera; Antonio Cuesta-Vargas; Juan Luis Garrido-Castro; Philip Gardiner; Clementina López-Medina; Pedro M Machado; Joan Condell; James Connolly; Jonathan Williams; Karla Munoz Esquivel; Tom O'Dwyer; M. Carmen Castro-Villegas; Cristina  González-Navas; Eduardo Collantes-Estévez

doi:10.3390/diagnostics10060426

Measuring spinal mobility using an inertial measurement unit system: a validation study in axial spondyloarthritis

I. Concepción Aranda-Valera
, Antonio Cuesta-Vargas
, Juan Luis Garrido-Castro
, Philip Gardiner
, Clementina López-Medina
, Pedro M Machado
, Joan Condell
, James Connolly
, Jonathan Williams
, Karla Munoz Esquivel
, Tom O'Dwyer
, M. Carmen Castro-Villegas
, Cristina González-Navas
, Eduardo Collantes-Estévez

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

61 Downloads (Pure)

Abstract

Portable inertial measurement units (IMUs) are beginning to be used in human motion analysis. These devices can be useful for the evaluation of spinal mobility in individuals with axial spondyloarthritis (axSpA). The objectives of this study were to assess (a) concurrent criterion validity in individuals with axSpA by comparing spinal mobility measured by an IMU sensor-based system vs. optical motion capture as the reference standard; (b) discriminant validity comparing mobility with healthy volunteers; (c) construct validity by comparing mobility results with relevant outcome measures. A total of 70 participants with axSpA and 20 healthy controls were included. Individuals with axSpA completed function and activity questionnaires, and their mobility was measured using conventional metrology for axSpA, an optical motion capture system, and an IMU sensor-based system. The UCOASMI, a metrology index based on measures obtained by motion capture, and the IUCOASMI, the same index using IMU measures, were also calculated. Descriptive and inferential analyses were conducted to show the relationships between outcome measures. There was excellent agreement (ICC > 0.90) between both systems and a significant correlation between the IUCOASMI and conventional metrology (r = 0.91), activity (r = 0.40), function (r = 0.62), quality of life (r = 0.55) and structural change (r = 0.76). This study demonstrates the validity of an IMU system to evaluate spinal mobility in axSpA. These systems are more feasible than optical motion capture systems, and they could be useful in clinical practice.

Original language	English
Article number	426
Number of pages	13
Journal	Diagnostics
Volume	10
Issue number	6
DOIs	https://doi.org/10.3390/diagnostics10060426
Publication status	Published (in print/issue) - 24 Jun 2020

Bibliographical note

Funding Information:
Funding: This work was supported by the Foundation for Research in Rheumatology (FOREUM), Consejería de Salud (Andalusian Government, Spain) grant PIN-0079-2016 and Instituto de Salud Carlos III grant DTS18/00046. The funding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of the data; in the writing of the manuscript; or in the decision to publish the results. Sensors were purchased from DorsaVi ltd. under a research agreement. DorsaVi had no input in the analysis or interpretation of the data. P.M.M. is supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the National Institutes of Health (NIH), (UK) National Health Service (NHS), the NIHR, or the (UK) Department of Health.

Publisher Copyright:
© 2020 MDPI AG. All rights reserved.

Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.

Funding Information:
This work was supported by the Foundation for Research in Rheumatology (FOREUM), Consejer?a de Salud (Andalusian Government, Spain) grant PIN-0079-2016 and Instituto de Salud Carlos III grant DTS18/00046. The funding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of the data; in the writing of the manuscript; or in the decision to publish the results. Sensors were purchased from DorsaVi ltd. under a research agreement. DorsaVi had no input in the analysis or interpretation of the data. P.M.M. is supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the National Institutes of Health (NIH), (UK) National Health Service (NHS), the NIHR, or the (UK) Department of Health.

Funding Information:
Funding: This work was supported by the Foundation for Research in Rheumatology (FOREUM), Consejería de Salud (Andalusian Government, Spain) grant PIN-0079-2016 and Instituto de Salud Carlos III grant DTS18/00046. The funding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of the data; in the writing of the manuscript; or in the decision to publish the results. Sensors were purchased from DorsaVi ltd. under a research agreement. DorsaVi had no input in the analysis or interpretation of the data. P.M.M. is supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the National Institutes of Health (NIH), (UK) National Health Service (NHS), the NIHR, or the (UK) Department of Health.

Publisher Copyright:
© 2020 MDPI AG. All rights reserved.

Funding

Funding Information: Funding: This work was supported by the Foundation for Research in Rheumatology (FOREUM), Consejería de Salud (Andalusian Government, Spain) grant PIN-0079-2016 and Instituto de Salud Carlos III grant DTS18/00046. The funding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of the data; in the writing of the manuscript; or in the decision to publish the results. Sensors were purchased from DorsaVi ltd. under a research agreement. DorsaVi had no input in the analysis or interpretation of the data. P.M.M. is supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the National Institutes of Health (NIH), (UK) National Health Service (NHS), the NIHR, or the (UK) Department of Health. Publisher Copyright: © 2020 MDPI AG. All rights reserved. Copyright: Copyright 2020 Elsevier B.V., All rights reserved. Funding Information: This work was supported by the Foundation for Research in Rheumatology (FOREUM), Consejer?a de Salud (Andalusian Government, Spain) grant PIN-0079-2016 and Instituto de Salud Carlos III grant DTS18/00046. The funding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of the data; in the writing of the manuscript; or in the decision to publish the results. Sensors were purchased from DorsaVi ltd. under a research agreement. DorsaVi had no input in the analysis or interpretation of the data. P.M.M. is supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the National Institutes of Health (NIH), (UK) National Health Service (NHS), the NIHR, or the (UK) Department of Health. Funding Information: Funding: This work was supported by the Foundation for Research in Rheumatology (FOREUM), Consejería de Salud (Andalusian Government, Spain) grant PIN-0079-2016 and Instituto de Salud Carlos III grant DTS18/00046. The funding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of the data; in the writing of the manuscript; or in the decision to publish the results. Sensors were purchased from DorsaVi ltd. under a research agreement. DorsaVi had no input in the analysis or interpretation of the data. P.M.M. is supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the National Institutes of Health (NIH), (UK) National Health Service (NHS), the NIHR, or the (UK) Department of Health. Publisher Copyright: © 2020 MDPI AG. All rights reserved.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Axial spondyloarthritis
Inertial measurement unit
Spinal mobility

Access to Document

10.3390/diagnostics10060426Licence: CC BY

diagnostics-10-00426Final published version, 733 KBLicence: CC BY

Cite this

Aranda-Valera, I. C., Cuesta-Vargas, A., Garrido-Castro, J. L., Gardiner, P., López-Medina, C., Machado, P. M., Condell, J., Connolly, J., Williams, J., Munoz Esquivel, K., O'Dwyer, T., Castro-Villegas, M. C., González-Navas, C., & Collantes-Estévez , E. (2020). Measuring spinal mobility using an inertial measurement unit system: a validation study in axial spondyloarthritis. Diagnostics, 10(6), Article 426. https://doi.org/10.3390/diagnostics10060426

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title = "Measuring spinal mobility using an inertial measurement unit system: a validation study in axial spondyloarthritis",

abstract = "Portable inertial measurement units (IMUs) are beginning to be used in human motion analysis. These devices can be useful for the evaluation of spinal mobility in individuals with axial spondyloarthritis (axSpA). The objectives of this study were to assess (a) concurrent criterion validity in individuals with axSpA by comparing spinal mobility measured by an IMU sensor-based system vs. optical motion capture as the reference standard; (b) discriminant validity comparing mobility with healthy volunteers; (c) construct validity by comparing mobility results with relevant outcome measures. A total of 70 participants with axSpA and 20 healthy controls were included. Individuals with axSpA completed function and activity questionnaires, and their mobility was measured using conventional metrology for axSpA, an optical motion capture system, and an IMU sensor-based system. The UCOASMI, a metrology index based on measures obtained by motion capture, and the IUCOASMI, the same index using IMU measures, were also calculated. Descriptive and inferential analyses were conducted to show the relationships between outcome measures. There was excellent agreement (ICC > 0.90) between both systems and a significant correlation between the IUCOASMI and conventional metrology (r = 0.91), activity (r = 0.40), function (r = 0.62), quality of life (r = 0.55) and structural change (r = 0.76). This study demonstrates the validity of an IMU system to evaluate spinal mobility in axSpA. These systems are more feasible than optical motion capture systems, and they could be useful in clinical practice.",

keywords = "Axial spondyloarthritis, Inertial measurement unit, Spinal mobility",

author = "Aranda-Valera, \{I. Concepci{\'o}n\} and Antonio Cuesta-Vargas and Garrido-Castro, \{Juan Luis\} and Philip Gardiner and Clementina L{\'o}pez-Medina and Machado, \{Pedro M\} and Joan Condell and James Connolly and Jonathan Williams and \{Munoz Esquivel\}, Karla and Tom O'Dwyer and Castro-Villegas, \{M. Carmen\} and Cristina Gonz{\'a}lez-Navas and Eduardo Collantes-Est{\'e}vez",

note = "Funding Information: Funding: This work was supported by the Foundation for Research in Rheumatology (FOREUM), Consejer{\'i}a de Salud (Andalusian Government, Spain) grant PIN-0079-2016 and Instituto de Salud Carlos III grant DTS18/00046. The funding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of the data; in the writing of the manuscript; or in the decision to publish the results. Sensors were purchased from DorsaVi ltd. under a research agreement. DorsaVi had no input in the analysis or interpretation of the data. P.M.M. is supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the National Institutes of Health (NIH), (UK) National Health Service (NHS), the NIHR, or the (UK) Department of Health. Publisher Copyright: {\textcopyright} 2020 MDPI AG. All rights reserved. Copyright: Copyright 2020 Elsevier B.V., All rights reserved. Funding Information: This work was supported by the Foundation for Research in Rheumatology (FOREUM), Consejer?a de Salud (Andalusian Government, Spain) grant PIN-0079-2016 and Instituto de Salud Carlos III grant DTS18/00046. The funding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of the data; in the writing of the manuscript; or in the decision to publish the results. Sensors were purchased from DorsaVi ltd. under a research agreement. DorsaVi had no input in the analysis or interpretation of the data. P.M.M. is supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the National Institutes of Health (NIH), (UK) National Health Service (NHS), the NIHR, or the (UK) Department of Health. Funding Information: Funding: This work was supported by the Foundation for Research in Rheumatology (FOREUM), Consejer{\'i}a de Salud (Andalusian Government, Spain) grant PIN-0079-2016 and Instituto de Salud Carlos III grant DTS18/00046. The funding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of the data; in the writing of the manuscript; or in the decision to publish the results. Sensors were purchased from DorsaVi ltd. under a research agreement. DorsaVi had no input in the analysis or interpretation of the data. P.M.M. is supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the National Institutes of Health (NIH), (UK) National Health Service (NHS), the NIHR, or the (UK) Department of Health. Publisher Copyright: {\textcopyright} 2020 MDPI AG. All rights reserved.",

year = "2020",

month = jun,

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doi = "10.3390/diagnostics10060426",

language = "English",

volume = "10",

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Aranda-Valera, IC, Cuesta-Vargas, A, Garrido-Castro, JL, Gardiner, P, López-Medina, C, Machado, PM, Condell, J, Connolly, J, Williams, J, Munoz Esquivel, K, O'Dwyer, T, Castro-Villegas, MC, González-Navas, C & Collantes-Estévez , E 2020, 'Measuring spinal mobility using an inertial measurement unit system: a validation study in axial spondyloarthritis', Diagnostics, vol. 10, no. 6, 426. https://doi.org/10.3390/diagnostics10060426

TY - JOUR

T1 - Measuring spinal mobility using an inertial measurement unit system: a validation study in axial spondyloarthritis

AU - Aranda-Valera, I. Concepción

AU - Cuesta-Vargas, Antonio

AU - Garrido-Castro, Juan Luis

AU - Gardiner, Philip

AU - López-Medina, Clementina

AU - Machado, Pedro M

AU - Condell, Joan

AU - Connolly, James

AU - Williams, Jonathan

AU - Munoz Esquivel, Karla

AU - O'Dwyer, Tom

AU - Castro-Villegas, M. Carmen

AU - González-Navas, Cristina

AU - Collantes-Estévez , Eduardo

N1 - Funding Information: Funding: This work was supported by the Foundation for Research in Rheumatology (FOREUM), Consejería de Salud (Andalusian Government, Spain) grant PIN-0079-2016 and Instituto de Salud Carlos III grant DTS18/00046. The funding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of the data; in the writing of the manuscript; or in the decision to publish the results. Sensors were purchased from DorsaVi ltd. under a research agreement. DorsaVi had no input in the analysis or interpretation of the data. P.M.M. is supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the National Institutes of Health (NIH), (UK) National Health Service (NHS), the NIHR, or the (UK) Department of Health. Publisher Copyright: © 2020 MDPI AG. All rights reserved. Copyright: Copyright 2020 Elsevier B.V., All rights reserved. Funding Information: This work was supported by the Foundation for Research in Rheumatology (FOREUM), Consejer?a de Salud (Andalusian Government, Spain) grant PIN-0079-2016 and Instituto de Salud Carlos III grant DTS18/00046. The funding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of the data; in the writing of the manuscript; or in the decision to publish the results. Sensors were purchased from DorsaVi ltd. under a research agreement. DorsaVi had no input in the analysis or interpretation of the data. P.M.M. is supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the National Institutes of Health (NIH), (UK) National Health Service (NHS), the NIHR, or the (UK) Department of Health. Funding Information: Funding: This work was supported by the Foundation for Research in Rheumatology (FOREUM), Consejería de Salud (Andalusian Government, Spain) grant PIN-0079-2016 and Instituto de Salud Carlos III grant DTS18/00046. The funding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of the data; in the writing of the manuscript; or in the decision to publish the results. Sensors were purchased from DorsaVi ltd. under a research agreement. DorsaVi had no input in the analysis or interpretation of the data. P.M.M. is supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the National Institutes of Health (NIH), (UK) National Health Service (NHS), the NIHR, or the (UK) Department of Health. Publisher Copyright: © 2020 MDPI AG. All rights reserved.

PY - 2020/6/24

Y1 - 2020/6/24

N2 - Portable inertial measurement units (IMUs) are beginning to be used in human motion analysis. These devices can be useful for the evaluation of spinal mobility in individuals with axial spondyloarthritis (axSpA). The objectives of this study were to assess (a) concurrent criterion validity in individuals with axSpA by comparing spinal mobility measured by an IMU sensor-based system vs. optical motion capture as the reference standard; (b) discriminant validity comparing mobility with healthy volunteers; (c) construct validity by comparing mobility results with relevant outcome measures. A total of 70 participants with axSpA and 20 healthy controls were included. Individuals with axSpA completed function and activity questionnaires, and their mobility was measured using conventional metrology for axSpA, an optical motion capture system, and an IMU sensor-based system. The UCOASMI, a metrology index based on measures obtained by motion capture, and the IUCOASMI, the same index using IMU measures, were also calculated. Descriptive and inferential analyses were conducted to show the relationships between outcome measures. There was excellent agreement (ICC > 0.90) between both systems and a significant correlation between the IUCOASMI and conventional metrology (r = 0.91), activity (r = 0.40), function (r = 0.62), quality of life (r = 0.55) and structural change (r = 0.76). This study demonstrates the validity of an IMU system to evaluate spinal mobility in axSpA. These systems are more feasible than optical motion capture systems, and they could be useful in clinical practice.

AB - Portable inertial measurement units (IMUs) are beginning to be used in human motion analysis. These devices can be useful for the evaluation of spinal mobility in individuals with axial spondyloarthritis (axSpA). The objectives of this study were to assess (a) concurrent criterion validity in individuals with axSpA by comparing spinal mobility measured by an IMU sensor-based system vs. optical motion capture as the reference standard; (b) discriminant validity comparing mobility with healthy volunteers; (c) construct validity by comparing mobility results with relevant outcome measures. A total of 70 participants with axSpA and 20 healthy controls were included. Individuals with axSpA completed function and activity questionnaires, and their mobility was measured using conventional metrology for axSpA, an optical motion capture system, and an IMU sensor-based system. The UCOASMI, a metrology index based on measures obtained by motion capture, and the IUCOASMI, the same index using IMU measures, were also calculated. Descriptive and inferential analyses were conducted to show the relationships between outcome measures. There was excellent agreement (ICC > 0.90) between both systems and a significant correlation between the IUCOASMI and conventional metrology (r = 0.91), activity (r = 0.40), function (r = 0.62), quality of life (r = 0.55) and structural change (r = 0.76). This study demonstrates the validity of an IMU system to evaluate spinal mobility in axSpA. These systems are more feasible than optical motion capture systems, and they could be useful in clinical practice.

KW - Axial spondyloarthritis

KW - Inertial measurement unit

KW - Spinal mobility

UR - https://www.scopus.com/pages/publications/85088249766

U2 - 10.3390/diagnostics10060426

DO - 10.3390/diagnostics10060426

M3 - Article

C2 - 32599741

SN - 2075-4418

VL - 10

JO - Diagnostics

JF - Diagnostics

IS - 6

M1 - 426

ER -

Measuring spinal mobility using an inertial measurement unit system: a validation study in axial spondyloarthritis

Abstract

Bibliographical note

Funding

UN SDGs

Keywords

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