Mathematical models of cell cycle regulation

H Fuss, Werner Dubitzky, Stephen Downes, MJ Kurth

    Research output: Contribution to journalArticle

    19 Citations (Scopus)

    Abstract

    The cell division cycle is a fundamental process of cell biology and a detailed understanding of its function, regulation and other underlying mechanisms is critical to many applications in biotechnology and medicine. Since a comprehensive analysis of the molecular mechanisms involved is too complex to be performed intuitively, mathematical and computational modelling techniques are essential. This paper is a review and analysis of recent approaches attempting to model cell cycle regulation by means of protein-protein interaction networks.
    LanguageEnglish
    Pages163-177
    JournalBriefings in Bioinformatics
    Volume6
    Issue number2
    Publication statusPublished - Jun 2005

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    Cell Cycle
    Theoretical Models
    Protein Interaction Maps
    Biotechnology
    Cell Biology
    Medicine
    Proteins

    Cite this

    Fuss, H., Dubitzky, W., Downes, S., & Kurth, MJ. (2005). Mathematical models of cell cycle regulation. Briefings in Bioinformatics, 6(2), 163-177.
    Fuss, H ; Dubitzky, Werner ; Downes, Stephen ; Kurth, MJ. / Mathematical models of cell cycle regulation. In: Briefings in Bioinformatics. 2005 ; Vol. 6, No. 2. pp. 163-177.
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    Fuss, H, Dubitzky, W, Downes, S & Kurth, MJ 2005, 'Mathematical models of cell cycle regulation', Briefings in Bioinformatics, vol. 6, no. 2, pp. 163-177.

    Mathematical models of cell cycle regulation. / Fuss, H; Dubitzky, Werner; Downes, Stephen; Kurth, MJ.

    In: Briefings in Bioinformatics, Vol. 6, No. 2, 06.2005, p. 163-177.

    Research output: Contribution to journalArticle

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    AB - The cell division cycle is a fundamental process of cell biology and a detailed understanding of its function, regulation and other underlying mechanisms is critical to many applications in biotechnology and medicine. Since a comprehensive analysis of the molecular mechanisms involved is too complex to be performed intuitively, mathematical and computational modelling techniques are essential. This paper is a review and analysis of recent approaches attempting to model cell cycle regulation by means of protein-protein interaction networks.

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    Fuss H, Dubitzky W, Downes S, Kurth MJ. Mathematical models of cell cycle regulation. Briefings in Bioinformatics. 2005 Jun;6(2):163-177.