Mathematical models of cell cycle regulation

H Fuss, Werner Dubitzky, Stephen Downes, MJ Kurth

    Research output: Contribution to journalArticle

    20 Citations (Scopus)

    Abstract

    The cell division cycle is a fundamental process of cell biology and a detailed understanding of its function, regulation and other underlying mechanisms is critical to many applications in biotechnology and medicine. Since a comprehensive analysis of the molecular mechanisms involved is too complex to be performed intuitively, mathematical and computational modelling techniques are essential. This paper is a review and analysis of recent approaches attempting to model cell cycle regulation by means of protein-protein interaction networks.
    Original languageEnglish
    Pages (from-to)163-177
    JournalBriefings in Bioinformatics
    Volume6
    Issue number2
    Publication statusPublished - Jun 2005

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    Fuss, H., Dubitzky, W., Downes, S., & Kurth, MJ. (2005). Mathematical models of cell cycle regulation. Briefings in Bioinformatics, 6(2), 163-177.