Low-dose vitamin B-6 lowers fasting plasma homocysteine levels in healthy elderly persons who are folate and riboflavin replete

MC McKinley, H McNulty, J McPartlin, JJ Strain, K Pentieva, M Ward, DG Weir, JM Scott

Research output: Contribution to journal › Article

Abstract

Background: Current data suggest that physiologic doses of vitamin B-6 have no significant homocysteine-lowering effect. It is possible that an effect of vitamin B-6 was missed in previous trials because of a much greater effect of folic acid, vitamin B-12, or both.Objective: The aim of this study was to investigate the effect of low-dose vitamin B-6 supplementation on fasting total homocysteine (tHcy) concentrations in healthy elderly persons who were made replete with folate and riboflavin.
LanguageEnglish
Pages759-764
JournalAmerican Journal of Clinical Nutrition
Volume73
Publication statusPublished - 2001

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Vitamin B 6
Riboflavin
Homocysteine
Folic Acid
Fasting
Vitamin B 12

Keywords

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Cite this

McKinley, MC ; McNulty, H ; McPartlin, J ; Strain, JJ ; Pentieva, K ; Ward, M ; Weir, DG ; Scott, JM. / Low-dose vitamin B-6 lowers fasting plasma homocysteine levels in healthy elderly persons who are folate and riboflavin replete. In: American Journal of Clinical Nutrition. 2001 ; Vol. 73. pp. 759-764.
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McKinley, MC, McNulty, H, McPartlin, J, Strain, JJ, Pentieva, K, Ward, M, Weir, DG & Scott, JM 2001, 'Low-dose vitamin B-6 lowers fasting plasma homocysteine levels in healthy elderly persons who are folate and riboflavin replete', American Journal of Clinical Nutrition, vol. 73, pp. 759-764.

Low-dose vitamin B-6 lowers fasting plasma homocysteine levels in healthy elderly persons who are folate and riboflavin replete. / McKinley, MC; McNulty, H; McPartlin, J; Strain, JJ; Pentieva, K; Ward, M; Weir, DG; Scott, JM.

In: American Journal of Clinical Nutrition, Vol. 73, 2001, p. 759-764.

Research output: Contribution to journal › Article

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T1 - Low-dose vitamin B-6 lowers fasting plasma homocysteine levels in healthy elderly persons who are folate and riboflavin replete

AU - McKinley, MC

AU - McNulty, H

AU - McPartlin, J

AU - Strain, JJ

AU - Pentieva, K

AU - Ward, M

AU - Weir, DG

AU - Scott, JM

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AB - Background: Current data suggest that physiologic doses of vitamin B-6 have no significant homocysteine-lowering effect. It is possible that an effect of vitamin B-6 was missed in previous trials because of a much greater effect of folic acid, vitamin B-12, or both.Objective: The aim of this study was to investigate the effect of low-dose vitamin B-6 supplementation on fasting total homocysteine (tHcy) concentrations in healthy elderly persons who were made replete with folate and riboflavin.

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M3 - Article

VL - 73

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JO - American Journal of Clinical Nutrition

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JF - American Journal of Clinical Nutrition

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McKinley MC, McNulty H, McPartlin J, Strain JJ, Pentieva K, Ward M et al. Low-dose vitamin B-6 lowers fasting plasma homocysteine levels in healthy elderly persons who are folate and riboflavin replete. American Journal of Clinical Nutrition. 2001;73:759-764.