Low-dose vitamin B-6 lowers fasting plasma homocysteine levels in healthy elderly persons who are folate and riboflavin replete

MC McKinley; H McNulty; J McPartlin; JJ Strain; K Pentieva; M Ward; DG Weir; JM Scott

Low-dose vitamin B-6 lowers fasting plasma homocysteine levels in healthy elderly persons who are folate and riboflavin replete

MC McKinley, H McNulty, J McPartlin, JJ Strain, K Pentieva, M Ward, DG Weir, JM Scott

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Current data suggest that physiologic doses of vitamin B-6 have no significant homocysteine-lowering effect. It is possible that an effect of vitamin B-6 was missed in previous trials because of a much greater effect of folic acid, vitamin B-12, or both.Objective: The aim of this study was to investigate the effect of low-dose vitamin B-6 supplementation on fasting total homocysteine (tHcy) concentrations in healthy elderly persons who were made replete with folate and riboflavin.

Original language	English
Pages (from-to)	759-764
Journal	American Journal of Clinical Nutrition
Volume	73
Publication status	Published - 2001

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title = "Low-dose vitamin B-6 lowers fasting plasma homocysteine levels in healthy elderly persons who are folate and riboflavin replete",

abstract = "Background: Current data suggest that physiologic doses of vitamin B-6 have no significant homocysteine-lowering effect. It is possible that an effect of vitamin B-6 was missed in previous trials because of a much greater effect of folic acid, vitamin B-12, or both.Objective: The aim of this study was to investigate the effect of low-dose vitamin B-6 supplementation on fasting total homocysteine (tHcy) concentrations in healthy elderly persons who were made replete with folate and riboflavin.",

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author = "MC McKinley and H McNulty and J McPartlin and JJ Strain and K Pentieva and M Ward and DG Weir and JM Scott",

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language = "English",

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pages = "759--764",

journal = "American Journal of Clinical Nutrition",

issn = "0002-9165",

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T1 - Low-dose vitamin B-6 lowers fasting plasma homocysteine levels in healthy elderly persons who are folate and riboflavin replete

AU - McKinley, MC

AU - McNulty, H

AU - McPartlin, J

AU - Strain, JJ

AU - Pentieva, K

AU - Ward, M

AU - Weir, DG

AU - Scott, JM

PY - 2001

Y1 - 2001

N2 - Background: Current data suggest that physiologic doses of vitamin B-6 have no significant homocysteine-lowering effect. It is possible that an effect of vitamin B-6 was missed in previous trials because of a much greater effect of folic acid, vitamin B-12, or both.Objective: The aim of this study was to investigate the effect of low-dose vitamin B-6 supplementation on fasting total homocysteine (tHcy) concentrations in healthy elderly persons who were made replete with folate and riboflavin.

AB - Background: Current data suggest that physiologic doses of vitamin B-6 have no significant homocysteine-lowering effect. It is possible that an effect of vitamin B-6 was missed in previous trials because of a much greater effect of folic acid, vitamin B-12, or both.Objective: The aim of this study was to investigate the effect of low-dose vitamin B-6 supplementation on fasting total homocysteine (tHcy) concentrations in healthy elderly persons who were made replete with folate and riboflavin.

KW - n/a

M3 - Article

VL - 73

SP - 759

EP - 764

JO - American Journal of Clinical Nutrition

JF - American Journal of Clinical Nutrition

SN - 0002-9165

ER -

Low-dose vitamin B-6 lowers fasting plasma homocysteine levels in healthy elderly persons who are folate and riboflavin replete

Abstract

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