@article{f44b9239d4584460b5ea20b08953bc44,
title = "Longitudinal study of spherical refractive error in infantilenystagmus syndrome",
abstract = "Purpose: To explore the onset and progression of spherical refractive error in a population with infantile nystagmus syndrome.Methods: Retrospective refractive error data were obtained from 147 medical records of children with infantile nystagmus syndrome (albinism n=98; idiopathic infantile nystagmus n=49), attending a low vision clinic in Northern Ireland, over a 24 year period (1986-2010). Data were categorised by age to allow for comparisons with published studies. A prospective group of participants with INS (n=22 [albinism n=18, idiopathic infantile nystagmus n=4]) (aged 0-4 years) were also recruited. Cycloplegic streak retinoscopy was performed biannually, over a three year period. Spherical equivalent refractive error and most ametropic meridian were analysed.Results: The mean spherical equivalent refractive errors for albinism and idiopathic infantile nystagmus groups (across all age categories) were hypermetropic, with highest levels demonstrated by the participants with albinism aged 1≤4 years (Mann-Whitney U test, p=0.013). Mean most ametropic meridian was highest in the albinism group aged 1≤12 years (Mann-Whitney U test, p",
keywords = "nystagmus, emmetropisation, vision, refractive error, children",
author = "Natasha Healey and Julie McClelland and Kathryn Saunders and Jonathan Jackson",
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year = "2014",
month = "1",
day = "22",
doi = "10.1111/opo.12117",
language = "English",
volume = "34",
pages = "369--375",
journal = "Ophthalmic and Physiological Optics: the Journal of the College of Optometrists",
issn = "0275-5408",
number = "3",
}