Logic based mapping of promoter enhancer regions of HPV16 and Interferon-γ: a search for similarity.

The complexity of virus–host interactions arises from the ability of both the host cell and the virus to utilize a variety of strategies to control each other during infection. Cellular transcription factors that are recruited by both the host cells and viruses play a key role in the performance of their functions. Here we compiled the literature on transcription factors that are involved in the regulation of interferon-γ gene expression and in the enhancement of the long control region of the human papillomavirus16, presenting this information in two logic-based diagrams using the System Biology Graphical Notation (SBGN) scheme.