Linkage mapping of the [Pro2]somatostatin-14 gene in zebrafish: Evolutionary perspectives

Hervé Tostivint; Lucille Joly; Isabelle Lihrmann; J. Michael Conlon; Marc Ekker; Hubert Vaudry

doi:10.1196/annals.1327.098

Linkage mapping of the [Pro²]somatostatin-14 gene in zebrafish: Evolutionary perspectives

Hervé Tostivint, Lucille Joly, Isabelle Lihrmann, J. Michael Conlon, Marc Ekker, Hubert Vaudry

School of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Radiation hybrid mapping assigned the zebrafish [Pro²] somatostatin-14 (also termed somatostatin 2; SS2) gene to linkage group 23 of the zebrafish genome, close to the marker nadl1.2. Comparative genomic analysis revealed conserved syntenies of the SS2 gene locus with part of the human 1p36 region, where the cortistatin gene is located. This observation strongly suggests that the SS2 gene in nonmammalian species and the cortistatin gene in mammals are orthologous.

Original language	English
Pages (from-to)	486-489
Number of pages	4
Journal	Annals of the New York Academy of Sciences
Volume	1040
DOIs	https://doi.org/10.1196/annals.1327.098
Publication status	Published (in print/issue) - 2005

Keywords

Comparative genomics
Cortistatin
Evolution
Radiation hybrid mapping
Somatostatin
Zebrafish

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10.1196/annals.1327.098

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title = "Linkage mapping of the [Pro2]somatostatin-14 gene in zebrafish: Evolutionary perspectives",

abstract = "Radiation hybrid mapping assigned the zebrafish [Pro2] somatostatin-14 (also termed somatostatin 2; SS2) gene to linkage group 23 of the zebrafish genome, close to the marker nadl1.2. Comparative genomic analysis revealed conserved syntenies of the SS2 gene locus with part of the human 1p36 region, where the cortistatin gene is located. This observation strongly suggests that the SS2 gene in nonmammalian species and the cortistatin gene in mammals are orthologous.",

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T2 - Evolutionary perspectives

AU - Tostivint, Hervé

AU - Joly, Lucille

AU - Lihrmann, Isabelle

AU - Conlon, J. Michael

AU - Ekker, Marc

AU - Vaudry, Hubert

PY - 2005

Y1 - 2005

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AB - Radiation hybrid mapping assigned the zebrafish [Pro2] somatostatin-14 (also termed somatostatin 2; SS2) gene to linkage group 23 of the zebrafish genome, close to the marker nadl1.2. Comparative genomic analysis revealed conserved syntenies of the SS2 gene locus with part of the human 1p36 region, where the cortistatin gene is located. This observation strongly suggests that the SS2 gene in nonmammalian species and the cortistatin gene in mammals are orthologous.

KW - Comparative genomics

KW - Cortistatin

KW - Evolution

KW - Radiation hybrid mapping

KW - Somatostatin

KW - Zebrafish

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SP - 486

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JO - Annals of the New York Academy of Sciences

JF - Annals of the New York Academy of Sciences

ER -

Linkage mapping of the [Pro²]somatostatin-14 gene in zebrafish: Evolutionary perspectives

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Keywords

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