Late potential analysis in Chagas disease using the vector spectral combination of orthogonal leads

R Bravo, OJ Escalona, F Mora, G Passariello

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Chagas disease is a major public health problem in South American countries, In the Venezuelan case, the heart is the mainly affected organ. The parasite that produces the disease takes the myocardium, causes muscle and conduction system degeneration, leading to abnormal ventricular contractility and conduction. Late potential (LP) analysis can detect abnormal electric behavior of the ventricles, which has been correlated with the presence of ventricular tachycardia episodes, Time domain methods for LP analysis are widely used but they are affected by other cardiac pathologies, i.e., branch blocks (BB), which are found simultaneously with abnormal ventricular conduction phenomena in chagasic patients. The use of an orthogonal lead vectorspectral combination using the Hartley transform has demonstrated to be a simple frequency domain method for the interpretation of abnormal ventricular potentials, This work uses the latter approach for LP analysis of high resolution ECG (HRECG) records of chagasic patients. The vectorspectral magnitude (S) was computed as the sum of the DHT spectra components of the XYZ leads in the frequency bands of 60 to 300Hz and -300 to -60Hz, for each chagasic patient group and a healthy subject control group in a time window at the end of QRS, Results showed that S is significantly lower in healthy subjects (63.5 +/- 23.8 mu V) than in chagasic patients with abnormal electrocardiogram (89.2 +/- 43.7 mu V), p<0.05. The vector spectral analysis is a simple frequency domain method for LP study, the results showed that the method can detect positive patients with generalized myocardial disease.
Original languageEnglish
Title of host publicationUnknown Host Publication
PublisherIEEE
Pages78-80
Number of pages3
Volume19
ISBN (Print)0-7803-4262-3
DOIs
Publication statusPublished - 15 Nov 1997
Event19TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY - Chicago, IL, USA.
Duration: 15 Nov 1997 → …

Publication series

NamePROCEEDINGS OF ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY
PublisherIEEE
ISSN (Electronic)1094-687X

Conference

Conference19TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY
Period15/11/97 → …

Keywords

  • Late potentials
  • ECG
  • Hartley transform
  • Chagas disease diagnosis
  • cardiomyopathy
  • vector spectrum
  • orthogonal leads.

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    Bravo, R., Escalona, OJ., Mora, F., & Passariello, G. (1997). Late potential analysis in Chagas disease using the vector spectral combination of orthogonal leads. In Unknown Host Publication (Vol. 19, pp. 78-80). (PROCEEDINGS OF ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY). IEEE. https://doi.org/10.1109/IEMBS.1997.754468