Label free detection of Prostate Specific Antigen at a screen printed immunosensor modified with a nano-structured gold layer

Sean rawlinson, Prosper Kanyong, Aaron McConville, John-Joe Fearon, James McLaughlin, James Davis

Research output: Contribution to journalArticle

1 Citation (Scopus)
4 Downloads (Pure)

Abstract

The development of a disposable immunosensor based on a hybrid gold-carbon screen printed electrode array is described. The electrodeposition of gold is shown to lead to a field of nanocrystals that facilitates antibody immobilization and enhances electron transfer. A label free analysis protocol based on ferrocyanide has been developed for the detection of Prostate Specific Antigen in the fg/mL range.
Original languageEnglish
Pages (from-to)1728-1731
Number of pages4
JournalChemistry Letters
Volume46
Issue number12
Early online date1 Nov 2017
DOIs
Publication statusPublished - 2017

Keywords

  • PSA
  • Prostate Cancer
  • Sensor
  • Electrode

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