Label free detection of Prostate Specific Antigen at a screen printed immunosensor modified with a nano-structured gold layer

Sean rawlinson; Prosper Kanyong; Aaron McConville; John-Joe Fearon; James McLaughlin; James Davis

doi:10.1246/cl.170790

Label free detection of Prostate Specific Antigen at a screen printed immunosensor modified with a nano-structured gold layer

Sean rawlinson, Prosper Kanyong, Aaron McConville, John-Joe Fearon, James McLaughlin, James Davis

Research output: Contribution to journal › Article › peer-review

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Abstract

The development of a disposable immunosensor based on a hybrid gold-carbon screen printed electrode array is described. The electrodeposition of gold is shown to lead to a field of nanocrystals that facilitates antibody immobilization and enhances electron transfer. A label free analysis protocol based on ferrocyanide has been developed for the detection of Prostate Specific Antigen in the fg/mL range.

Original language	English
Pages (from-to)	1728-1731
Number of pages	4
Journal	Chemistry Letters
Volume	46
Issue number	12
Early online date	1 Nov 2017
DOIs	https://doi.org/10.1246/cl.170790
Publication status	Published (in print/issue) - 2017

Keywords

PSA
Prostate Cancer
Sensor
Electrode

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1246/cl.170790

Rawlinson Chemistry Letters PSAFinal published version, 2.61 MB

Cite this

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title = "Label free detection of Prostate Specific Antigen at a screen printed immunosensor modified with a nano-structured gold layer",

abstract = "The development of a disposable immunosensor based on a hybrid gold-carbon screen printed electrode array is described. The electrodeposition of gold is shown to lead to a field of nanocrystals that facilitates antibody immobilization and enhances electron transfer. A label free analysis protocol based on ferrocyanide has been developed for the detection of Prostate Specific Antigen in the fg/mL range.",

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AU - McConville, Aaron

AU - Fearon, John-Joe

AU - McLaughlin, James

AU - Davis, James

PY - 2017

Y1 - 2017

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AB - The development of a disposable immunosensor based on a hybrid gold-carbon screen printed electrode array is described. The electrodeposition of gold is shown to lead to a field of nanocrystals that facilitates antibody immobilization and enhances electron transfer. A label free analysis protocol based on ferrocyanide has been developed for the detection of Prostate Specific Antigen in the fg/mL range.

KW - PSA

KW - Prostate Cancer

KW - Sensor

KW - Electrode

UR - https://pure.ulster.ac.uk/en/publications/label-free-detection-of-prostate-specific-antigen-at-a-screen-pri

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DO - 10.1246/cl.170790

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JO - Chemistry Letters

JF - Chemistry Letters

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ER -

Label free detection of Prostate Specific Antigen at a screen printed immunosensor modified with a nano-structured gold layer

Abstract

Keywords

UN SDGs

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