Abstract
The ketone bodies acetoacetate and (R)-3-hydroxybutyrate (β-hydroxybutyrate) are catabolic products of free fatty acids produced during low glucose intake/availability. Ketogenesis, the production of ketone bodies, is mainly associated with starvation, type I diabetes, and certain weight loss regimens. Understanding the underlying chemistry of ketone body production can greatly enhance our understanding of various disease processes, including Alzheimer's disease, and lead to identification of new therapeutic compounds approved for use in human subjects.
| Original language | English |
|---|---|
| Title of host publication | Encyclopedia of Food and Health |
| Publisher | Elsevier |
| Pages | 483-489 |
| Number of pages | 7 |
| ISBN (Print) | 9780123849533 |
| DOIs | |
| Publication status | Published (in print/issue) - 2016 |
Bibliographical note
Copyright © 2016 Elsevier Ltd. All rights reserved.UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Acetoacetate
- Acetone
- Atkins diet
- Ketogenesis
- Ketogenic diets
- Ketolysis
- Ketonuria
- Rothera reaction
- Starvation
- β-Hydroxybutyrate
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