The ketone bodies acetoacetate and (R)-3-hydroxybutyrate (β-hydroxybutyrate) are catabolic products of free fatty acids produced during low glucose intake/availability. Ketogenesis, the production of ketone bodies, is mainly associated with starvation, type I diabetes, and certain weight loss regimens. Understanding the underlying chemistry of ketone body production can greatly enhance our understanding of various disease processes, including Alzheimer's disease, and lead to identification of new therapeutic compounds approved for use in human subjects.
|Title of host publication||Encyclopedia of Food and Health|
|Number of pages||7|
|Publication status||Published (in print/issue) - 2016|
Bibliographical noteCopyright © 2016 Elsevier Ltd. All rights reserved.
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