Janus particle synthesis: Via aligned non-concentric angular nozzles and electrohydrodynamic co-flow for tunable drug release

Chunchen Zhang, Ming Wei Chang, Yudong Li, Yuankai Qi, Jingwen Wu, Zeeshan Ahmad, Jing Song Li

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

A novel non-concentric, symmetrical spinneret possessing aligned nozzles with angular outlets was designed and manufactured. The device was used to synthesize Janus particles by atomizing co-flowing formulations at relatively high electric fields (up to ∼15 kV). By manipulating the nozzle outlet angle, the maximum applied voltage permitting stable co-jetting was enhanced; enabling the production of finer droplets and, thus, microparticles. Furthermore, non-concentric co-flow, process optimization and stable atomization yielded Janus particles with distinct morphological features which were then used to demonstrate tunable drug release.

Original languageEnglish
Pages (from-to)77174-77178
Number of pages5
JournalRSC Advances
Volume6
Issue number81
DOIs
Publication statusPublished - 9 Aug 2016

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