Janus particle synthesis: Via aligned non-concentric angular nozzles and electrohydrodynamic co-flow for tunable drug release

Chunchen Zhang, Ming Wei Chang, Yudong Li, Yuankai Qi, Jingwen Wu, Zeeshan Ahmad, Jing Song Li

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

A novel non-concentric, symmetrical spinneret possessing aligned nozzles with angular outlets was designed and manufactured. The device was used to synthesize Janus particles by atomizing co-flowing formulations at relatively high electric fields (up to ∼15 kV). By manipulating the nozzle outlet angle, the maximum applied voltage permitting stable co-jetting was enhanced; enabling the production of finer droplets and, thus, microparticles. Furthermore, non-concentric co-flow, process optimization and stable atomization yielded Janus particles with distinct morphological features which were then used to demonstrate tunable drug release.

LanguageEnglish
Pages77174-77178
Number of pages5
JournalRSC Advances
Volume6
Issue number81
DOIs
Publication statusPublished - 9 Aug 2016

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Electrohydrodynamics
Nozzles
Atomization
Pharmaceutical Preparations
Electric fields
Electric potential

Cite this

Zhang, Chunchen ; Chang, Ming Wei ; Li, Yudong ; Qi, Yuankai ; Wu, Jingwen ; Ahmad, Zeeshan ; Li, Jing Song. / Janus particle synthesis : Via aligned non-concentric angular nozzles and electrohydrodynamic co-flow for tunable drug release. In: RSC Advances. 2016 ; Vol. 6, No. 81. pp. 77174-77178.
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Janus particle synthesis : Via aligned non-concentric angular nozzles and electrohydrodynamic co-flow for tunable drug release. / Zhang, Chunchen; Chang, Ming Wei; Li, Yudong; Qi, Yuankai; Wu, Jingwen; Ahmad, Zeeshan; Li, Jing Song.

In: RSC Advances, Vol. 6, No. 81, 09.08.2016, p. 77174-77178.

Research output: Contribution to journalArticle

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T2 - RSC Advances

AU - Zhang, Chunchen

AU - Chang, Ming Wei

AU - Li, Yudong

AU - Qi, Yuankai

AU - Wu, Jingwen

AU - Ahmad, Zeeshan

AU - Li, Jing Song

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