Iodinated Cyanine Dyes: A New Class of Sensitisers for use in NIR Activated Photodynamic Therapy (PDT)

John Callan, Jordan Atchison, Sukanta Kamila, Kieran Logan, Dean Nicholas, Colin Fowley, James Davis, Bridgeen Callan, Anthony McHale

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

A new class of iodinated cyanine dyes have been prepared for use in NIR excited photodynamic therapy (PDT) and demonstrated improved efficacy in three pancreatic cell lines as well as excellent tumour control in a murine model of the disease.
LanguageEnglish
Pages2009-2012
JournalChemical Communications
Volume53
Issue number12
DOIs
Publication statusPublished - 18 Jan 2017

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Photodynamic therapy
Tumors
Coloring Agents
Dyes
Cells

Keywords

  • PDT
  • sensitiser
  • NIR
  • pancreatic cancer

Cite this

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title = "Iodinated Cyanine Dyes: A New Class of Sensitisers for use in NIR Activated Photodynamic Therapy (PDT)",
abstract = "A new class of iodinated cyanine dyes have been prepared for use in NIR excited photodynamic therapy (PDT) and demonstrated improved efficacy in three pancreatic cell lines as well as excellent tumour control in a murine model of the disease.",
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Iodinated Cyanine Dyes: A New Class of Sensitisers for use in NIR Activated Photodynamic Therapy (PDT). / Callan, John; Atchison, Jordan; Kamila, Sukanta; Logan, Kieran; Nicholas, Dean; Fowley, Colin; Davis, James; Callan, Bridgeen; McHale, Anthony.

In: Chemical Communications, Vol. 53, No. 12, 18.01.2017, p. 2009-2012.

Research output: Contribution to journalArticle

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T1 - Iodinated Cyanine Dyes: A New Class of Sensitisers for use in NIR Activated Photodynamic Therapy (PDT)

AU - Callan, John

AU - Atchison, Jordan

AU - Kamila, Sukanta

AU - Logan, Kieran

AU - Nicholas, Dean

AU - Fowley, Colin

AU - Davis, James

AU - Callan, Bridgeen

AU - McHale, Anthony

PY - 2017/1/18

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AB - A new class of iodinated cyanine dyes have been prepared for use in NIR excited photodynamic therapy (PDT) and demonstrated improved efficacy in three pancreatic cell lines as well as excellent tumour control in a murine model of the disease.

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KW - sensitiser

KW - NIR

KW - pancreatic cancer

U2 - 10.1039/C6CC09624G

DO - 10.1039/C6CC09624G

M3 - Article

VL - 53

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EP - 2012

JO - Chemical Communications

T2 - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

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