Iodinated Cyanine Dyes: A New Class of Sensitisers for use in NIR Activated Photodynamic Therapy (PDT)

John Callan; Jordan Atchison; Sukanta Kamila; Kieran Logan; Dean Nicholas; Colin Fowley; James Davis; Bridgeen Callan; Anthony McHale

doi:10.1039/C6CC09624G

Iodinated Cyanine Dyes: A New Class of Sensitisers for use in NIR Activated Photodynamic Therapy (PDT)

John Callan, Jordan Atchison, Sukanta Kamila, Kieran Logan, Dean Nicholas, Colin Fowley, James Davis, Bridgeen Callan, Anthony McHale

Research output: Contribution to journal › Article › peer-review

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Abstract

A new class of iodinated cyanine dyes have been prepared for use in NIR excited photodynamic therapy (PDT) and demonstrated improved efficacy in three pancreatic cell lines as well as excellent tumour control in a murine model of the disease.

Original language	English
Pages (from-to)	2009-2012
Journal	Chemical Communications
Volume	53
Issue number	12
DOIs	https://doi.org/10.1039/C6CC09624G
Publication status	Published (in print/issue) - 18 Jan 2017

Keywords

PDT
sensitiser
NIR
pancreatic cancer

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Cite this

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title = "Iodinated Cyanine Dyes: A New Class of Sensitisers for use in NIR Activated Photodynamic Therapy (PDT)",

abstract = "A new class of iodinated cyanine dyes have been prepared for use in NIR excited photodynamic therapy (PDT) and demonstrated improved efficacy in three pancreatic cell lines as well as excellent tumour control in a murine model of the disease.",

keywords = "PDT, sensitiser, NIR, pancreatic cancer",

author = "John Callan and Jordan Atchison and Sukanta Kamila and Kieran Logan and Dean Nicholas and Colin Fowley and James Davis and Bridgeen Callan and Anthony McHale",

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T1 - Iodinated Cyanine Dyes: A New Class of Sensitisers for use in NIR Activated Photodynamic Therapy (PDT)

AU - Callan, John

AU - Atchison, Jordan

AU - Kamila, Sukanta

AU - Logan, Kieran

AU - Nicholas, Dean

AU - Fowley, Colin

AU - Davis, James

AU - Callan, Bridgeen

AU - McHale, Anthony

PY - 2017/1/18

Y1 - 2017/1/18

N2 - A new class of iodinated cyanine dyes have been prepared for use in NIR excited photodynamic therapy (PDT) and demonstrated improved efficacy in three pancreatic cell lines as well as excellent tumour control in a murine model of the disease.

AB - A new class of iodinated cyanine dyes have been prepared for use in NIR excited photodynamic therapy (PDT) and demonstrated improved efficacy in three pancreatic cell lines as well as excellent tumour control in a murine model of the disease.

KW - PDT

KW - sensitiser

KW - NIR

KW - pancreatic cancer

U2 - 10.1039/C6CC09624G

DO - 10.1039/C6CC09624G

M3 - Article

SN - 1359-7345

VL - 53

SP - 2009

EP - 2012

JO - Chemical Communications

JF - Chemical Communications

IS - 12

ER -

Iodinated Cyanine Dyes: A New Class of Sensitisers for use in NIR Activated Photodynamic Therapy (PDT)

Abstract

Keywords

UN SDGs

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