Iodinated Cyanine Dyes: A New Class of Sensitisers for use in NIR Activated Photodynamic Therapy (PDT)

John Callan, Jordan Atchison, Sukanta Kamila, Kieran Logan, Dean Nicholas, Colin Fowley, James Davis, Bridgeen Callan, Anthony McHale

Research output: Contribution to journalArticle

45 Citations (Scopus)
33 Downloads (Pure)

Abstract

A new class of iodinated cyanine dyes have been prepared for use in NIR excited photodynamic therapy (PDT) and demonstrated improved efficacy in three pancreatic cell lines as well as excellent tumour control in a murine model of the disease.
Original languageEnglish
Pages (from-to)2009-2012
JournalChemical Communications
Volume53
Issue number12
DOIs
Publication statusPublished - 18 Jan 2017

Keywords

  • PDT
  • sensitiser
  • NIR
  • pancreatic cancer

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