A new class of iodinated cyanine dyes have been prepared for use in NIR excited photodynamic therapy (PDT) and demonstrated improved efficacy in three pancreatic cell lines as well as excellent tumour control in a murine model of the disease.
- pancreatic cancer
Callan, J., Atchison, J., Kamila, S., Logan, K., Nicholas, D., Fowley, C., Davis, J., Callan, B., & McHale, A. (2017). Iodinated Cyanine Dyes: A New Class of Sensitisers for use in NIR Activated Photodynamic Therapy (PDT). Chemical Communications, 53(12), 2009-2012. https://doi.org/10.1039/C6CC09624G