Investigation of the medium-term effects of Olibra (TM) fat emulsion on food intake in non-obese subjects

C. M. Logan, T. A. McCaffrey, Julie Wallace, P. J. Robson, Rob Welch, A. Dunne, Barbara Livingstone

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Objective: To investigate the effect of Olibra (TM) fat emulsion on medium-term food intake and appetite in non-obese subjects. Design: Double-blind, placebo-controlled, within-subject crossover. Setting: University of Ulster, Coleraine. Subjects: A total of 28 subjects (14 male, 14 female). Interventions: Subjects were randomly assigned to receive either a 200 g portion of test (5 g of Olibra (TM) fat) or control (5 g milk fat) yoghurt for breakfast for 2 x 3 week `study' phases, separated by a 3-week `wash-out' phase. On days 1, 8 and 22 of the study phases, food intake 4 h post-consumption of the yoghurt was assessed by pre- and post-covert weighing at an ad libitum buffet-style test lunch. Throughout each of these study days, appetite was assessed using visual analogue scales (VAS) at regular intervals. For the remainder of the study days, and the following 24 h ('post-study days'), subjects reported their food intake using weighed dietary records. Results: Consumption of the Olibra (TM) emulsion had no significant effect on mean energy, macronutrient or amounts of food consumed at the lunch 4 h post-consumption. Self-reported food intakes indicated that there was no significant effect of the emulsion on energy intakes for the remainder of each study day and post-study days. There was considerable individual variation in food intakes following consumption of the Olibra (TM) emulsion, with 46, 59 and 57% of subjects reducing their energy intakes at lunch on days 1, 8 and 22. There was no consistent effect of the emulsion on appetite ratings. Conclusions: In contrast to earlier studies, there was no evidence of a short- or medium-term effect of the Olibra (TM) emulsion on food intake or appetite. This could be owing to numerous confounding factors influencing eating behaviour and/or the different study design used in the present study.
LanguageEnglish
Pages1081-1091
JournalEuropean Journal of Clinical Nutrition
Volume60
Issue number9
DOIs
Publication statusPublished - Sep 2006

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Emulsions
Eating
Fats
Appetite
Lunch
Yogurt
Energy Intake
Diet Records
Breakfast
Feeding Behavior
Visual Analog Scale
Milk
Placebos
Food

Cite this

Logan, C. M. ; McCaffrey, T. A. ; Wallace, Julie ; Robson, P. J. ; Welch, Rob ; Dunne, A. ; Livingstone, Barbara. / Investigation of the medium-term effects of Olibra (TM) fat emulsion on food intake in non-obese subjects. In: European Journal of Clinical Nutrition. 2006 ; Vol. 60, No. 9. pp. 1081-1091.
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title = "Investigation of the medium-term effects of Olibra (TM) fat emulsion on food intake in non-obese subjects",
abstract = "Objective: To investigate the effect of Olibra (TM) fat emulsion on medium-term food intake and appetite in non-obese subjects. Design: Double-blind, placebo-controlled, within-subject crossover. Setting: University of Ulster, Coleraine. Subjects: A total of 28 subjects (14 male, 14 female). Interventions: Subjects were randomly assigned to receive either a 200 g portion of test (5 g of Olibra (TM) fat) or control (5 g milk fat) yoghurt for breakfast for 2 x 3 week `study' phases, separated by a 3-week `wash-out' phase. On days 1, 8 and 22 of the study phases, food intake 4 h post-consumption of the yoghurt was assessed by pre- and post-covert weighing at an ad libitum buffet-style test lunch. Throughout each of these study days, appetite was assessed using visual analogue scales (VAS) at regular intervals. For the remainder of the study days, and the following 24 h ('post-study days'), subjects reported their food intake using weighed dietary records. Results: Consumption of the Olibra (TM) emulsion had no significant effect on mean energy, macronutrient or amounts of food consumed at the lunch 4 h post-consumption. Self-reported food intakes indicated that there was no significant effect of the emulsion on energy intakes for the remainder of each study day and post-study days. There was considerable individual variation in food intakes following consumption of the Olibra (TM) emulsion, with 46, 59 and 57{\%} of subjects reducing their energy intakes at lunch on days 1, 8 and 22. There was no consistent effect of the emulsion on appetite ratings. Conclusions: In contrast to earlier studies, there was no evidence of a short- or medium-term effect of the Olibra (TM) emulsion on food intake or appetite. This could be owing to numerous confounding factors influencing eating behaviour and/or the different study design used in the present study.",
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Investigation of the medium-term effects of Olibra (TM) fat emulsion on food intake in non-obese subjects. / Logan, C. M.; McCaffrey, T. A.; Wallace, Julie; Robson, P. J.; Welch, Rob; Dunne, A.; Livingstone, Barbara.

In: European Journal of Clinical Nutrition, Vol. 60, No. 9, 09.2006, p. 1081-1091.

Research output: Contribution to journalArticle

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T1 - Investigation of the medium-term effects of Olibra (TM) fat emulsion on food intake in non-obese subjects

AU - Logan, C. M.

AU - McCaffrey, T. A.

AU - Wallace, Julie

AU - Robson, P. J.

AU - Welch, Rob

AU - Dunne, A.

AU - Livingstone, Barbara

PY - 2006/9

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N2 - Objective: To investigate the effect of Olibra (TM) fat emulsion on medium-term food intake and appetite in non-obese subjects. Design: Double-blind, placebo-controlled, within-subject crossover. Setting: University of Ulster, Coleraine. Subjects: A total of 28 subjects (14 male, 14 female). Interventions: Subjects were randomly assigned to receive either a 200 g portion of test (5 g of Olibra (TM) fat) or control (5 g milk fat) yoghurt for breakfast for 2 x 3 week `study' phases, separated by a 3-week `wash-out' phase. On days 1, 8 and 22 of the study phases, food intake 4 h post-consumption of the yoghurt was assessed by pre- and post-covert weighing at an ad libitum buffet-style test lunch. Throughout each of these study days, appetite was assessed using visual analogue scales (VAS) at regular intervals. For the remainder of the study days, and the following 24 h ('post-study days'), subjects reported their food intake using weighed dietary records. Results: Consumption of the Olibra (TM) emulsion had no significant effect on mean energy, macronutrient or amounts of food consumed at the lunch 4 h post-consumption. Self-reported food intakes indicated that there was no significant effect of the emulsion on energy intakes for the remainder of each study day and post-study days. There was considerable individual variation in food intakes following consumption of the Olibra (TM) emulsion, with 46, 59 and 57% of subjects reducing their energy intakes at lunch on days 1, 8 and 22. There was no consistent effect of the emulsion on appetite ratings. Conclusions: In contrast to earlier studies, there was no evidence of a short- or medium-term effect of the Olibra (TM) emulsion on food intake or appetite. This could be owing to numerous confounding factors influencing eating behaviour and/or the different study design used in the present study.

AB - Objective: To investigate the effect of Olibra (TM) fat emulsion on medium-term food intake and appetite in non-obese subjects. Design: Double-blind, placebo-controlled, within-subject crossover. Setting: University of Ulster, Coleraine. Subjects: A total of 28 subjects (14 male, 14 female). Interventions: Subjects were randomly assigned to receive either a 200 g portion of test (5 g of Olibra (TM) fat) or control (5 g milk fat) yoghurt for breakfast for 2 x 3 week `study' phases, separated by a 3-week `wash-out' phase. On days 1, 8 and 22 of the study phases, food intake 4 h post-consumption of the yoghurt was assessed by pre- and post-covert weighing at an ad libitum buffet-style test lunch. Throughout each of these study days, appetite was assessed using visual analogue scales (VAS) at regular intervals. For the remainder of the study days, and the following 24 h ('post-study days'), subjects reported their food intake using weighed dietary records. Results: Consumption of the Olibra (TM) emulsion had no significant effect on mean energy, macronutrient or amounts of food consumed at the lunch 4 h post-consumption. Self-reported food intakes indicated that there was no significant effect of the emulsion on energy intakes for the remainder of each study day and post-study days. There was considerable individual variation in food intakes following consumption of the Olibra (TM) emulsion, with 46, 59 and 57% of subjects reducing their energy intakes at lunch on days 1, 8 and 22. There was no consistent effect of the emulsion on appetite ratings. Conclusions: In contrast to earlier studies, there was no evidence of a short- or medium-term effect of the Olibra (TM) emulsion on food intake or appetite. This could be owing to numerous confounding factors influencing eating behaviour and/or the different study design used in the present study.

U2 - 10.1038/sj.ejcn.1602422

DO - 10.1038/sj.ejcn.1602422

M3 - Article

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SP - 1081

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JO - European Journal of Clinical Nutrition

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JF - European Journal of Clinical Nutrition

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