Insulin-releasing and cytotoxic properties of the frog skin peptide, tigerinin-1R: a structure-activity study

D Srinivasan; Opeolu Ojo; Yasser Abdel-Wahab; Peter Flatt; L Guilhaudis; JM Conlon

Insulin-releasing and cytotoxic properties of the frog skin peptide, tigerinin-1R: a structure-activity study

D Srinivasan, Opeolu Ojo, Yasser Abdel-Wahab, Peter Flatt, L Guilhaudis, JM Conlon

Research output: Contribution to journal › Article › peer-review

Abstract

insulin release and cytotoxicity of changes in cationicity and hydrophobicity produced by selected substitutions of amino acids by l-arginine, l-lysine and l-tryptophan. The [A5W], [L8W] and [I10W] analogs produced a significant (P

Original language	English
Pages (from-to)	23-31
Journal	Peptides
Volume	55
Publication status	Published (in print/issue) - 12 Feb 2014

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title = "Insulin-releasing and cytotoxic properties of the frog skin peptide, tigerinin-1R: a structure-activity study",

abstract = "insulin release and cytotoxicity of changes in cationicity and hydrophobicity produced by selected substitutions of amino acids by l-arginine, l-lysine and l-tryptophan. The [A5W], [L8W] and [I10W] analogs produced a significant (P",

author = "D Srinivasan and Opeolu Ojo and Yasser Abdel-Wahab and Peter Flatt and L Guilhaudis and JM Conlon",

year = "2014",

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T1 - Insulin-releasing and cytotoxic properties of the frog skin peptide, tigerinin-1R: a structure-activity study

AU - Srinivasan, D

AU - Ojo, Opeolu

AU - Abdel-Wahab, Yasser

AU - Flatt, Peter

AU - Guilhaudis, L

AU - Conlon, JM

PY - 2014/2/12

Y1 - 2014/2/12

N2 - insulin release and cytotoxicity of changes in cationicity and hydrophobicity produced by selected substitutions of amino acids by l-arginine, l-lysine and l-tryptophan. The [A5W], [L8W] and [I10W] analogs produced a significant (P

AB - insulin release and cytotoxicity of changes in cationicity and hydrophobicity produced by selected substitutions of amino acids by l-arginine, l-lysine and l-tryptophan. The [A5W], [L8W] and [I10W] analogs produced a significant (P

M3 - Article

SN - 1873-5169

VL - 55

SP - 23

EP - 31

JO - Peptides

JF - Peptides

ER -

Insulin-releasing and cytotoxic properties of the frog skin peptide, tigerinin-1R: a structure-activity study

Abstract

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