Insulin-releasing and cytotoxic properties of the frog skin peptide, tigerinin-1R: a structure-activity study

D Srinivasan, Opeolu Ojo, Yasser Abdel-Wahab, Peter Flatt, L Guilhaudis, JM Conlon

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

insulin release and cytotoxicity of changes in cationicity and hydrophobicity produced by selected substitutions of amino acids by l-arginine, l-lysine and l-tryptophan. The [A5W], [L8W] and [I10W] analogs produced a significant (P
Original languageEnglish
Pages (from-to)23-31
JournalPeptides
Volume55
Publication statusPublished - 12 Feb 2014

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