Influence of protein calorie malnutrition and fasting on the activities of δ-aminolevulinic acid dehydratase and porphobilinogen deaminase in rats

D.G. Adjarov, E.N. Naydenova, M.A. Kerimova, K Pentieva, L.B. Ivanova, A.V. Ivanova

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Rats were fed a restricted standard diet (6-8 g daily) for 4 weeks. The erythrocyte activity of delta-aminolevulinic acid dehydratase showed a very expressed decrease (7.9 times) and its hepatic activity diminished more than twice. Porphobilinogen deaminase activity was reduced by 40% and 17% respectively. After a 3-day total food deprivation delta-aminolevulinic acid dehydratase activity remained unchanged in red blood cells, but an increase by 52% was found in the liver. The erythrocyte activity of porphobilinogen deaminase was reduced by 42% and its hepatic activity--by 16%.
LanguageEnglish
Pages199-202
JournalExperimental and Toxicologic Pathology
Volume46
Issue number3
DOIs
Publication statusPublished - 1994

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Hydroxymethylbilane Synthase
Porphobilinogen Synthase
Protein-Energy Malnutrition
Rats
Fasting
Erythrocytes
Liver
Nutrition
Food Deprivation
Proteins
Blood
Cells
Diet

Keywords

  • protein calorie malnutrition
  • fasting
  • rats
  • δ-aminolevulinic acid dehydratase
  • porphobilinogen deaminase

Cite this

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title = "Influence of protein calorie malnutrition and fasting on the activities of δ-aminolevulinic acid dehydratase and porphobilinogen deaminase in rats",
abstract = "Rats were fed a restricted standard diet (6-8 g daily) for 4 weeks. The erythrocyte activity of delta-aminolevulinic acid dehydratase showed a very expressed decrease (7.9 times) and its hepatic activity diminished more than twice. Porphobilinogen deaminase activity was reduced by 40{\%} and 17{\%} respectively. After a 3-day total food deprivation delta-aminolevulinic acid dehydratase activity remained unchanged in red blood cells, but an increase by 52{\%} was found in the liver. The erythrocyte activity of porphobilinogen deaminase was reduced by 42{\%} and its hepatic activity--by 16{\%}.",
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Influence of protein calorie malnutrition and fasting on the activities of δ-aminolevulinic acid dehydratase and porphobilinogen deaminase in rats. / Adjarov, D.G.; Naydenova, E.N.; Kerimova, M.A.; Pentieva, K; Ivanova, L.B.; Ivanova, A.V.

In: Experimental and Toxicologic Pathology, Vol. 46, No. 3, 1994, p. 199-202.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Influence of protein calorie malnutrition and fasting on the activities of δ-aminolevulinic acid dehydratase and porphobilinogen deaminase in rats

AU - Adjarov, D.G.

AU - Naydenova, E.N.

AU - Kerimova, M.A.

AU - Pentieva, K

AU - Ivanova, L.B.

AU - Ivanova, A.V.

PY - 1994

Y1 - 1994

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AB - Rats were fed a restricted standard diet (6-8 g daily) for 4 weeks. The erythrocyte activity of delta-aminolevulinic acid dehydratase showed a very expressed decrease (7.9 times) and its hepatic activity diminished more than twice. Porphobilinogen deaminase activity was reduced by 40% and 17% respectively. After a 3-day total food deprivation delta-aminolevulinic acid dehydratase activity remained unchanged in red blood cells, but an increase by 52% was found in the liver. The erythrocyte activity of porphobilinogen deaminase was reduced by 42% and its hepatic activity--by 16%.

KW - protein calorie malnutrition

KW - fasting

KW - rats

KW - δ-aminolevulinic acid dehydratase

KW - porphobilinogen deaminase

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DO - 10.1016/S0940-2993(11)80081-3

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EP - 202

JO - Experimental and Toxicologic Pathology

T2 - Experimental and Toxicologic Pathology

JF - Experimental and Toxicologic Pathology

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