Rats were fed a restricted standard diet (6-8 g daily) for 4 weeks. The erythrocyte activity of delta-aminolevulinic acid dehydratase showed a very expressed decrease (7.9 times) and its hepatic activity diminished more than twice. Porphobilinogen deaminase activity was reduced by 40% and 17% respectively. After a 3-day total food deprivation delta-aminolevulinic acid dehydratase activity remained unchanged in red blood cells, but an increase by 52% was found in the liver. The erythrocyte activity of porphobilinogen deaminase was reduced by 42% and its hepatic activity--by 16%.
- protein calorie malnutrition
- δ-aminolevulinic acid dehydratase
- porphobilinogen deaminase
Adjarov, D. G., Naydenova, E. N., Kerimova, M. A., Pentieva, K., Ivanova, L. B., & Ivanova, A. V. (1994). Influence of protein calorie malnutrition and fasting on the activities of δ-aminolevulinic acid dehydratase and porphobilinogen deaminase in rats. Experimental and Toxicologic Pathology, 46(3), 199-202. https://doi.org/10.1016/S0940-2993(11)80081-3