Influence of protein calorie malnutrition and fasting on the activities of δ-aminolevulinic acid dehydratase and porphobilinogen deaminase in rats

D.G. Adjarov, E.N. Naydenova, M.A. Kerimova, K Pentieva, L.B. Ivanova, A.V. Ivanova

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Rats were fed a restricted standard diet (6-8 g daily) for 4 weeks. The erythrocyte activity of delta-aminolevulinic acid dehydratase showed a very expressed decrease (7.9 times) and its hepatic activity diminished more than twice. Porphobilinogen deaminase activity was reduced by 40% and 17% respectively. After a 3-day total food deprivation delta-aminolevulinic acid dehydratase activity remained unchanged in red blood cells, but an increase by 52% was found in the liver. The erythrocyte activity of porphobilinogen deaminase was reduced by 42% and its hepatic activity--by 16%.
Original languageEnglish
Pages (from-to)199-202
JournalExperimental and Toxicologic Pathology
Volume46
Issue number3
DOIs
Publication statusPublished - 1994

Keywords

  • protein calorie malnutrition
  • fasting
  • rats
  • δ-aminolevulinic acid dehydratase
  • porphobilinogen deaminase

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