Infantile hypertrophic pyloric stenosis: A comparative study of incidence and other epidemiological characteristics in seven European regions.

RN Perersen, E Garne, Maria Loane, L Korsholm, S Husby, Working Group EUROCAT

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Objective. The objective of this study was to present epidemiologic data on infantile hypertrophic pyloric stenosis (IHPS) from seven well-defined European regions, and to compare incidence and changes in incidence over time between these regions. Methods. This was a population-based study using data from registries of congenital malformations (EUROCAT) for a period of more than two decades (1980-2002). Results. A total of 2534 infants were diagnosed with IHPS during the study period, giving an overall incidence of IHPS of 2.0 per 1000 live births (LB), ranging from 0.86 per 1000 LB to 3.96 per 1000 LB in the seven regions. A significant decrease in incidence was observed in two regions and a significant increase in incidence was observed in two other regions. Young maternal age (
Original languageEnglish
Pages (from-to)599-604
JournalJournal of Maternal-Fetal and Neonatal Medicine
Issue number9
Publication statusPublished - 2008


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