1 Acute and chronic mechanisms of action of novel insulinotropic antidiabetic drug, BTS 67 582 (1,1-dimethyl-2-(2-morpholinophenyl)guanidin fumarate), were examined in the stable cultured BRIN-BD11 cell line. 2 BTS67582 (100-400 mu M) stimulated a concentration-dependent increase (P
|Journal||British Journal of Pharmacology|
|Publication status||Published - May 2000|
McClenaghan, N., Ball, AJ., & Flatt, P. (2000). Induced desensitization of the insulinotropic effects of antidiabetic drugs, BTS 67 582 and tolbutamide. British Journal of Pharmacology, 130(2), 478-484.