In vitro Modulation of Pancreatic Insulin Secretion and Extra Pancreatic Insulin Action, Enzymatic Starch Digestion and Protein Glycation by Terminalia chebula Extracts

V Kasabri; Peter Flatt; YHA Abdel-Wahab

doi:10.9734/EJMP/2014/8496

In vitro Modulation of Pancreatic Insulin Secretion and Extra Pancreatic Insulin Action, Enzymatic Starch Digestion and Protein Glycation by Terminalia chebula Extracts

Research output: Contribution to journal › Article › peer-review

Abstract

Aim: Traditional plant treatments have been used throughout the world for the therapy of diabetes mellitus. Study Design: Using multiple in vitro models; this study was designed to investigate the efficacy and mode of action of Terminalia chebula Retz. (Combretaceae) used traditionally for treatment of diabetes. Place and Duration of Study: School of Biomedical Sciences, University of Ulster, 2001-2004. Results: T. chebula aqueous extract stimulated basal insulin output and potentiated glucose-stimulated insulin secretion concentration-dependently in the clonal pancreatic beta cell line, BRIN-BD11 (p

Original language	English
Pages (from-to)	771-782
Journal	European Journal of Medicinal Plants
Volume	4
Issue number	7
DOIs	https://doi.org/10.9734/EJMP/2014/8496
Publication status	Published (in print/issue) - 20 Mar 2014

Keywords

Terminilia chebula Retz. (Combretaceae)
insulin secretion
insulin action
starch digestion
peptide glycation.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.9734/EJMP/2014/8496

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title = "In vitro Modulation of Pancreatic Insulin Secretion and Extra Pancreatic Insulin Action, Enzymatic Starch Digestion and Protein Glycation by Terminalia chebula Extracts",

abstract = "Aim: Traditional plant treatments have been used throughout the world for the therapy of diabetes mellitus. Study Design: Using multiple in vitro models; this study was designed to investigate the efficacy and mode of action of Terminalia chebula Retz. (Combretaceae) used traditionally for treatment of diabetes. Place and Duration of Study: School of Biomedical Sciences, University of Ulster, 2001-2004. Results: T. chebula aqueous extract stimulated basal insulin output and potentiated glucose-stimulated insulin secretion concentration-dependently in the clonal pancreatic beta cell line, BRIN-BD11 (p",

keywords = "Terminilia chebula Retz. (Combretaceae), insulin secretion, insulin action, starch digestion, peptide glycation.",

author = "V Kasabri and Peter Flatt and YHA Abdel-Wahab",

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AU - Flatt, Peter

AU - Abdel-Wahab, YHA

PY - 2014/3/20

Y1 - 2014/3/20

N2 - Aim: Traditional plant treatments have been used throughout the world for the therapy of diabetes mellitus. Study Design: Using multiple in vitro models; this study was designed to investigate the efficacy and mode of action of Terminalia chebula Retz. (Combretaceae) used traditionally for treatment of diabetes. Place and Duration of Study: School of Biomedical Sciences, University of Ulster, 2001-2004. Results: T. chebula aqueous extract stimulated basal insulin output and potentiated glucose-stimulated insulin secretion concentration-dependently in the clonal pancreatic beta cell line, BRIN-BD11 (p

AB - Aim: Traditional plant treatments have been used throughout the world for the therapy of diabetes mellitus. Study Design: Using multiple in vitro models; this study was designed to investigate the efficacy and mode of action of Terminalia chebula Retz. (Combretaceae) used traditionally for treatment of diabetes. Place and Duration of Study: School of Biomedical Sciences, University of Ulster, 2001-2004. Results: T. chebula aqueous extract stimulated basal insulin output and potentiated glucose-stimulated insulin secretion concentration-dependently in the clonal pancreatic beta cell line, BRIN-BD11 (p

KW - Terminilia chebula Retz. (Combretaceae)

KW - insulin secretion

KW - insulin action

KW - starch digestion

KW - peptide glycation.

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JO - European Journal of Medicinal Plants

JF - European Journal of Medicinal Plants

IS - 7

ER -

In vitro Modulation of Pancreatic Insulin Secretion and Extra Pancreatic Insulin Action, Enzymatic Starch Digestion and Protein Glycation by Terminalia chebula Extracts

Abstract

Keywords

UN SDGs

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