Impedimetric Point of Care Cardiac Marker System

E Hamad, E McAdams, JAD McLaughlin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The requirement for fast identification, with accurate and reliable diagnostics for acute myocardial infarction or “Heart Attack” has generated what can be called “Point-of-Care (POC)” devices.This paper will use key engineering platforms developed that can address the need for improved clinical management in cardiology and reduce Health Service delivery costs. Our primary objective is to develop rapid and label-free Point of Care diagnostic tests for cardiac markers based on multi-frequency impedimetric transducers.Impedance testing using micro-scale interdigitated electrodes (μIDE’s) offers a much more rapid response compared to the reaction times of fluorescent label-based systems (~ 8 minutes). In the case of small gap of IDE impedance, we are seeing stable and predictive trends occurring after one minute. Therefore the overall benefit to the clinician and patient will be true point of care monitoring allowing a blood sample to be rapidly (1-2 minutes) analysed for a range of cardiac enzymes.
LanguageEnglish
Title of host publicationUnknown Host Publication
Number of pages4
Volume37
Publication statusPublished - 2010
EventComputing in Cardiology - Belfast-UK
Duration: 1 Jan 2010 → …

Conference

ConferenceComputing in Cardiology
Period1/01/10 → …

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Point-of-Care Systems
Electric Impedance
Myocardial Infarction
Cardiology
Transducers
Routine Diagnostic Tests
Reaction Time
Health Services
Electrodes
Costs and Cost Analysis
Equipment and Supplies
Enzymes

Cite this

Hamad, E., McAdams, E., & McLaughlin, JAD. (2010). Impedimetric Point of Care Cardiac Marker System. In Unknown Host Publication (Vol. 37)
Hamad, E ; McAdams, E ; McLaughlin, JAD. / Impedimetric Point of Care Cardiac Marker System. Unknown Host Publication. Vol. 37 2010.
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title = "Impedimetric Point of Care Cardiac Marker System",
abstract = "The requirement for fast identification, with accurate and reliable diagnostics for acute myocardial infarction or “Heart Attack” has generated what can be called “Point-of-Care (POC)” devices.This paper will use key engineering platforms developed that can address the need for improved clinical management in cardiology and reduce Health Service delivery costs. Our primary objective is to develop rapid and label-free Point of Care diagnostic tests for cardiac markers based on multi-frequency impedimetric transducers.Impedance testing using micro-scale interdigitated electrodes (μIDE’s) offers a much more rapid response compared to the reaction times of fluorescent label-based systems (~ 8 minutes). In the case of small gap of IDE impedance, we are seeing stable and predictive trends occurring after one minute. Therefore the overall benefit to the clinician and patient will be true point of care monitoring allowing a blood sample to be rapidly (1-2 minutes) analysed for a range of cardiac enzymes.",
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Hamad, E, McAdams, E & McLaughlin, JAD 2010, Impedimetric Point of Care Cardiac Marker System. in Unknown Host Publication. vol. 37, Computing in Cardiology, 1/01/10.

Impedimetric Point of Care Cardiac Marker System. / Hamad, E; McAdams, E; McLaughlin, JAD.

Unknown Host Publication. Vol. 37 2010.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

TY - GEN

T1 - Impedimetric Point of Care Cardiac Marker System

AU - Hamad, E

AU - McAdams, E

AU - McLaughlin, JAD

PY - 2010

Y1 - 2010

N2 - The requirement for fast identification, with accurate and reliable diagnostics for acute myocardial infarction or “Heart Attack” has generated what can be called “Point-of-Care (POC)” devices.This paper will use key engineering platforms developed that can address the need for improved clinical management in cardiology and reduce Health Service delivery costs. Our primary objective is to develop rapid and label-free Point of Care diagnostic tests for cardiac markers based on multi-frequency impedimetric transducers.Impedance testing using micro-scale interdigitated electrodes (μIDE’s) offers a much more rapid response compared to the reaction times of fluorescent label-based systems (~ 8 minutes). In the case of small gap of IDE impedance, we are seeing stable and predictive trends occurring after one minute. Therefore the overall benefit to the clinician and patient will be true point of care monitoring allowing a blood sample to be rapidly (1-2 minutes) analysed for a range of cardiac enzymes.

AB - The requirement for fast identification, with accurate and reliable diagnostics for acute myocardial infarction or “Heart Attack” has generated what can be called “Point-of-Care (POC)” devices.This paper will use key engineering platforms developed that can address the need for improved clinical management in cardiology and reduce Health Service delivery costs. Our primary objective is to develop rapid and label-free Point of Care diagnostic tests for cardiac markers based on multi-frequency impedimetric transducers.Impedance testing using micro-scale interdigitated electrodes (μIDE’s) offers a much more rapid response compared to the reaction times of fluorescent label-based systems (~ 8 minutes). In the case of small gap of IDE impedance, we are seeing stable and predictive trends occurring after one minute. Therefore the overall benefit to the clinician and patient will be true point of care monitoring allowing a blood sample to be rapidly (1-2 minutes) analysed for a range of cardiac enzymes.

M3 - Conference contribution

VL - 37

BT - Unknown Host Publication

ER -

Hamad E, McAdams E, McLaughlin JAD. Impedimetric Point of Care Cardiac Marker System. In Unknown Host Publication. Vol. 37. 2010