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Identifying and overcoming barriers to referral in advanced heart failure. A scientific statement of the Heart Failure Association ( HFA ) of the ESC

  • Guillaume Baudry
  • , Maria Generosa Crespo‐Leiro
  • , Clément Delmas
  • , Federica Guidetti
  • , Marta Jimenez‐Blanco Bravo
  • , Federica Valente
  • , Maja Cikes
  • , Nicolas Girerd
  • , Finn Gustafsson
  • , Gianluigi Savarese
  • , Linda W. van Laake
  • , Loreena Hill
  • , Anne Kathrine Skibelund
  • , Andreas Zuckermann
  • , Marco Metra
  • , Kevin Damman

Research output: Contribution to journalArticlepeer-review

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Abstract

The identification of patients with advanced heart failure (HF) remains challenging, often leading to delayed referrals and suboptimal use of advanced therapies such as long-term mechanical circulatory support (MCS) or heart transplantation (HT). This delay contributes to worse outcomes and missed opportunities for timely intervention. Many eligible patients are not recognized early enough in their clinical trajectory, either due to the complexity of the condition, overlapping HF phenotypes, or limited awareness of referral criteria among non-specialist clinicians. In this context, the aim of this scientific statement from the Heart Failure Association (HFA) of the ESC is to systematically identify and address the multifaceted barriers that hinder early recognition and referral for advanced HF care. These barriers span across different stakeholders—patients, caregivers, referring physicians, HF specialists, the academic community, and health authorities. The document proposes practical, stakeholder-specific solutions to improve awareness, standardize referral criteria, integrate digital decision-support tools, and structure care networks. Ultimately, the goal is to enable earlier access to specialized evaluation, ensure equitable use of HT and MCS when appropriate, and improve both survival and quality of life for patients living with advanced HF.
Original languageEnglish
Pages (from-to)3312-3325
Number of pages14
JournalEuropean Journal of Heart Failure
Volume27
Issue number12
Early online date17 Aug 2025
DOIs
Publication statusPublished (in print/issue) - 1 Dec 2025

Bibliographical note

© 2025 The Author(s). European Journal of Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.

Keywords

  • Advanced heart failure
  • Referral
  • Quality of care centres
  • Heart transplantation
  • Mechanical circulatory support
  • Societies, Medical
  • Humans
  • Quality of Life
  • Heart Failure/therapy
  • Referral and Consultation/standards

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