Abstract
A tri-compartment centrifugal electrospinning system (TCCES) was designed and used to fabricate multiple fiber membranes (from individual polyvinyl pyrrolidone (PVP), thermoplastic polyurethane (TPU) and poly-methyl methacrylate (PMMA) fibers). Controlled engineering of membrane composition presents opportunities to control mechanical and water contact angle characteristics. Furthermore, control on drug release rate is achieved based on active hosting fiber type contributing towards the overall membrane. The current system enables a high degree of alignment, production rate and variations to composition, indicating clear potential in biomedical fields requiring the use of encapsulated or embedded drug in membrane materials.
| Original language | English |
|---|---|
| Pages (from-to) | 53-59 |
| Number of pages | 7 |
| Journal | Materials Today Communications |
| Volume | 17 |
| Early online date | 18 Aug 2018 |
| DOIs | |
| Publication status | Published (in print/issue) - 1 Dec 2018 |
Funding
This work was financially supported by the National Nature Science Foundation of China (No. 81771960 ), the Fundamental Research Funds for the Central Universities ( 2017QNA5017 ) and Key Technologies R&D Program of Zhejiang Province ( 2015C02035 ).
Keywords
- Alignment
- Centrifugal electrospinning
- Composite fibers
- Drug release
- Regulation
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