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High resolution corneal and single pulse imaging with line field spectral domain optical coherence tomography

  • Samuel Lawman
  • , Yue Dong
  • , Bryan M. Williams
  • , Vito Romano
  • , Stephen Kaye
  • , Simon P. Harding
  • , Colin Willoughby
  • , Yao-Chun Shen
  • , Yalin Zheng

Research output: Contribution to journal › Article › peer-review

158 Downloads (Pure)

Abstract

We report the development of a Spectral Domain Line Field Optical Coherence Tomography (LF-OCT) system, using a broad bandwidth and spatial coherent Super-Continuum (SC) source. With conventional quasi-Continuous Wave (CW) setup we achieve axial resolutions up to 2.1 μm in air and 3D volume imaging speeds up to 213 kA-Scan/s. Furthermore, we report the use of a single SC pulse, of 2 ns duration, to temporally gate an OCT B-Scan image of 70 A-Scans. This is the equivalent of 35 GA-Scans/s. We apply the CW setup for high resolution imaging of the fine structures of a human cornea sample ex-vivo. The single pulse setup is applied to imaging of a coated pharmaceutical tablet. The fixed pattern noise due to spectral noise is removed by subtracting the median magnitude A-Scan. We also demonstrate that the Fourier phase can be used to remove aberration caused artefacts.
Original languageEnglish
Pages (from-to)12395
JournalOptics Express
Volume24
Issue number11
DOIs
Publication statusAccepted - 23 May 2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • OCT
  • cornea
  • imaging

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