Hexose recognition by insulin-secreting BRIN-BD11 cells

Neville McClenaghan, Alison Gallagher, CR Barnett, Peter Flatt

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Clonal BRIN-BD11 cells were produced by electrofusion of NEDH rat islet B-cells with immortal RINm5F cells. Western blotting analysis revealed that unlike RINm5F, novel BRIN-BD11 cells expressed high levels of the glucose transport protein GLUT-2, coupled with a rapid and sustained uptake for D-glucose, significantly greater than RINm5F after only 5 min (p
Original languageEnglish
Pages (from-to)724-728
JournalBiochemical and Biophysical Research Communications
Volume223
Issue number3
Publication statusPublished - Jun 1996

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