TY - JOUR
T1 - HED (Hypohidrotic Ectodermal Dysplasia)
T2 - A Review
AU - Callea, Michele
AU - Scalisi, Francisco Cammarata
AU - Yavuz, Izzet
AU - Dogan, Mehmet Sinan
AU - Willoughby, Colin Eric
AU - Bashyam, Murali Dharan
N1 - Publisher Copyright:
© 2021, Journal of International Dental and Medical Research, All Rights Reserved.
PY - 2021/4/30
Y1 - 2021/4/30
N2 - Abstract The ectodermal dysplasias (EDs) are a heterogeneous group of inherited, developmental disorders characterized by alterations in two or more ectodermal structures including the hair, teeth, nails and sweat glands. Currently, more than 200 types of ectodermal dysplasias have been described. Anhidrotic or hypohidrotic ectodermal dysplasia (AED/HED), the most common ED, is characterized by three cardinal features: hypotrichosis, hypohidrosis and hypodontia. We review the genetic and pathogenetic mechanisms of AED/HED and report on the management of clinical manifestations driven by embryology, anatomy and physiology.
AB - Abstract The ectodermal dysplasias (EDs) are a heterogeneous group of inherited, developmental disorders characterized by alterations in two or more ectodermal structures including the hair, teeth, nails and sweat glands. Currently, more than 200 types of ectodermal dysplasias have been described. Anhidrotic or hypohidrotic ectodermal dysplasia (AED/HED), the most common ED, is characterized by three cardinal features: hypotrichosis, hypohidrosis and hypodontia. We review the genetic and pathogenetic mechanisms of AED/HED and report on the management of clinical manifestations driven by embryology, anatomy and physiology.
KW - Anhidrotic or hypohidrotic ectodermal dysplasia
KW - clinical
KW - Ectodermal dysplasias
KW - ethiopathogenesis
UR - http://www.scopus.com/inward/record.url?scp=85110678843&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85110678843
VL - 14
SP - 785
EP - 789
JO - Journal of International Dental and Medical Research
JF - Journal of International Dental and Medical Research
SN - 1309-100X
IS - 2
ER -