HED (Hypohidrotic Ectodermal Dysplasia): A Review

Michele Callea; Francisco Cammarata Scalisi; Izzet Yavuz; Mehmet Sinan Dogan; Colin Eric Willoughby; Murali Dharan Bashyam

HED (Hypohidrotic Ectodermal Dysplasia): A Review

Michele Callea, Francisco Cammarata Scalisi, Izzet Yavuz, Mehmet Sinan Dogan, Colin Eric Willoughby, Murali Dharan Bashyam

Centre for Genomic Medicine

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Abstract

The ectodermal dysplasias (EDs) are a heterogeneous group of inherited, developmental disorders characterized by alterations in two or more ectodermal structures including the hair, teeth, nails and sweat glands. Currently, more than 200 types of ectodermal dysplasias have been described. Anhidrotic or hypohidrotic ectodermal dysplasia (AED/HED), the most common ED, is characterized by three cardinal features: hypotrichosis, hypohidrosis and hypodontia. We review the genetic and pathogenetic mechanisms of AED/HED and report on the management of clinical manifestations driven by embryology, anatomy and physiology.

Original language	English
Pages (from-to)	785-789
Number of pages	5
Journal	Journal of International Dental and Medical Research
Volume	14
Issue number	2
Publication status	Published (in print/issue) - 30 Apr 2021

Bibliographical note

Publisher Copyright:
© 2021, Journal of International Dental and Medical Research, All Rights Reserved.

Keywords

Anhidrotic or hypohidrotic ectodermal dysplasia
clinical
Ectodermal dysplasias
ethiopathogenesis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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57-D21_1470_Michele_Callea_Italy-1Final published version, 179 KBLicence: Unspecified

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AU - Bashyam, Murali Dharan

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HED (Hypohidrotic Ectodermal Dysplasia): A Review

Abstract

Bibliographical note

Keywords

UN SDGs

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