HED (Hypohidrotic Ectodermal Dysplasia): A Review

Michele Callea, Francisco Cammarata Scalisi, Izzet Yavuz, Mehmet Sinan Dogan, Colin Eric Willoughby, Murali Dharan Bashyam

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)
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Abstract

The ectodermal dysplasias (EDs) are a heterogeneous group of inherited, developmental disorders characterized by alterations in two or more ectodermal structures including the hair, teeth, nails and sweat glands. Currently, more than 200 types of ectodermal dysplasias have been described. Anhidrotic or hypohidrotic ectodermal dysplasia (AED/HED), the most common ED, is characterized by three cardinal features: hypotrichosis, hypohidrosis and hypodontia. We review the genetic and pathogenetic mechanisms of AED/HED and report on the management of clinical manifestations driven by embryology, anatomy and physiology.

Original languageEnglish
Pages (from-to)785-789
Number of pages5
JournalJournal of International Dental and Medical Research
Volume14
Issue number2
Publication statusPublished (in print/issue) - 30 Apr 2021

Bibliographical note

Publisher Copyright:
© 2021, Journal of International Dental and Medical Research, All Rights Reserved.

Keywords

  • Anhidrotic or hypohidrotic ectodermal dysplasia
  • clinical
  • Ectodermal dysplasias
  • ethiopathogenesis

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