Hall’s Effect Based Sensing Mechanism for Nano Super Paramagnetic Particle-Protein Complex Structure

Danny Wen Yaw Chung, Nikhil Bhalla, Hsi-Wen Li, Yi Ying Ye, Hao Chun Yang, Dorota G. Pijanowska

Research output: Contribution to conferencePaper

Abstract

In this work sensing mechanism for nanomagnetic particles (nano size magnetic beads) bounded with protein complex has been studied. The methodology employed involves formation of antibody-protein complex, similar to the one formed in sandwiched ELISA (Enzyme Linked Immunosorbent Assay), which is bounded to super paramagnetic particle instead of enzyme to detect the presence of protein molecule. Hall's sensor was fabricated using 0.35 m BioMEMS TSMC technology which senses the magnetic field from the beads. The investigation covers Hall's effect simulations, magneto static analysis of forces on nano magnetic beads, mechanical modeling of bead-protein complex and discussion on fabrication of Hall's Sensor. The design also shows the inductive coil on the top the Hall's sensor that is used to magnetize the beads.
Original languageEnglish
DOIs
Publication statusPublished - Jul 2012
Event IEEE-Asia Pacific Conference on Transducers APCOT - Nanjing, China
Duration: 10 Jul 2012 → …

Conference

Conference IEEE-Asia Pacific Conference on Transducers APCOT
CountryChina
CityNanjing
Period10/07/12 → …

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    Chung, D. W. Y., Bhalla, N., Li, H-W., Ye, Y. Y., Yang, H. C., & Pijanowska, D. G. (2012). Hall’s Effect Based Sensing Mechanism for Nano Super Paramagnetic Particle-Protein Complex Structure. Paper presented at IEEE-Asia Pacific Conference on Transducers APCOT, Nanjing, China. https://doi.org/10.13140/2.1.3415.7449