Hall’s Effect Based Sensing Mechanism for Nano Super Paramagnetic Particle-Protein Complex Structure

Danny Wen Yaw Chung, Nikhil Bhalla, Hsi-Wen Li, Yi Ying Ye, Hao Chun Yang, Dorota G. Pijanowska

Research output: Contribution to conferencePaper

Abstract

In this work sensing mechanism for nanomagnetic particles (nano size magnetic beads) bounded with protein complex has been studied. The methodology employed involves formation of antibody-protein complex, similar to the one formed in sandwiched ELISA (Enzyme Linked Immunosorbent Assay), which is bounded to super paramagnetic particle instead of enzyme to detect the presence of protein molecule. Hall's sensor was fabricated using 0.35 m BioMEMS TSMC technology which senses the magnetic field from the beads. The investigation covers Hall's effect simulations, magneto static analysis of forces on nano magnetic beads, mechanical modeling of bead-protein complex and discussion on fabrication of Hall's Sensor. The design also shows the inductive coil on the top the Hall's sensor that is used to magnetize the beads.

Conference

Conference IEEE-Asia Pacific Conference on Transducers APCOT
CountryChina
CityNanjing
Period10/07/12 → …

Fingerprint

Hall effect
Proteins
Sensors
BioMEMS
Nanomagnetics
Enzymes
Static analysis
Antibodies
Assays
Magnetic fields
Fabrication
Molecules

Cite this

Chung, D. W. Y., Bhalla, N., Li, H-W., Ye, Y. Y., Yang, H. C., & Pijanowska, D. G. (2012). Hall’s Effect Based Sensing Mechanism for Nano Super Paramagnetic Particle-Protein Complex Structure. Paper presented at IEEE-Asia Pacific Conference on Transducers APCOT, Nanjing, China. https://doi.org/10.13140/2.1.3415.7449
Chung, Danny Wen Yaw ; Bhalla, Nikhil ; Li, Hsi-Wen ; Ye, Yi Ying ; Yang, Hao Chun ; Pijanowska, Dorota G. / Hall’s Effect Based Sensing Mechanism for Nano Super Paramagnetic Particle-Protein Complex Structure. Paper presented at IEEE-Asia Pacific Conference on Transducers APCOT, Nanjing, China.
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title = "Hall’s Effect Based Sensing Mechanism for Nano Super Paramagnetic Particle-Protein Complex Structure",
abstract = "In this work sensing mechanism for nanomagnetic particles (nano size magnetic beads) bounded with protein complex has been studied. The methodology employed involves formation of antibody-protein complex, similar to the one formed in sandwiched ELISA (Enzyme Linked Immunosorbent Assay), which is bounded to super paramagnetic particle instead of enzyme to detect the presence of protein molecule. Hall's sensor was fabricated using 0.35 m BioMEMS TSMC technology which senses the magnetic field from the beads. The investigation covers Hall's effect simulations, magneto static analysis of forces on nano magnetic beads, mechanical modeling of bead-protein complex and discussion on fabrication of Hall's Sensor. The design also shows the inductive coil on the top the Hall's sensor that is used to magnetize the beads.",
author = "Chung, {Danny Wen Yaw} and Nikhil Bhalla and Hsi-Wen Li and Ye, {Yi Ying} and Yang, {Hao Chun} and Pijanowska, {Dorota G.}",
year = "2012",
month = "7",
doi = "10.13140/2.1.3415.7449",
language = "English",
note = "IEEE-Asia Pacific Conference on Transducers APCOT ; Conference date: 10-07-2012",

}

Chung, DWY, Bhalla, N, Li, H-W, Ye, YY, Yang, HC & Pijanowska, DG 2012, 'Hall’s Effect Based Sensing Mechanism for Nano Super Paramagnetic Particle-Protein Complex Structure' Paper presented at IEEE-Asia Pacific Conference on Transducers APCOT, Nanjing, China, 10/07/12, . https://doi.org/10.13140/2.1.3415.7449

Hall’s Effect Based Sensing Mechanism for Nano Super Paramagnetic Particle-Protein Complex Structure. / Chung, Danny Wen Yaw; Bhalla, Nikhil; Li, Hsi-Wen; Ye, Yi Ying; Yang, Hao Chun; Pijanowska, Dorota G.

2012. Paper presented at IEEE-Asia Pacific Conference on Transducers APCOT, Nanjing, China.

Research output: Contribution to conferencePaper

TY - CONF

T1 - Hall’s Effect Based Sensing Mechanism for Nano Super Paramagnetic Particle-Protein Complex Structure

AU - Chung, Danny Wen Yaw

AU - Bhalla, Nikhil

AU - Li, Hsi-Wen

AU - Ye, Yi Ying

AU - Yang, Hao Chun

AU - Pijanowska, Dorota G.

PY - 2012/7

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N2 - In this work sensing mechanism for nanomagnetic particles (nano size magnetic beads) bounded with protein complex has been studied. The methodology employed involves formation of antibody-protein complex, similar to the one formed in sandwiched ELISA (Enzyme Linked Immunosorbent Assay), which is bounded to super paramagnetic particle instead of enzyme to detect the presence of protein molecule. Hall's sensor was fabricated using 0.35 m BioMEMS TSMC technology which senses the magnetic field from the beads. The investigation covers Hall's effect simulations, magneto static analysis of forces on nano magnetic beads, mechanical modeling of bead-protein complex and discussion on fabrication of Hall's Sensor. The design also shows the inductive coil on the top the Hall's sensor that is used to magnetize the beads.

AB - In this work sensing mechanism for nanomagnetic particles (nano size magnetic beads) bounded with protein complex has been studied. The methodology employed involves formation of antibody-protein complex, similar to the one formed in sandwiched ELISA (Enzyme Linked Immunosorbent Assay), which is bounded to super paramagnetic particle instead of enzyme to detect the presence of protein molecule. Hall's sensor was fabricated using 0.35 m BioMEMS TSMC technology which senses the magnetic field from the beads. The investigation covers Hall's effect simulations, magneto static analysis of forces on nano magnetic beads, mechanical modeling of bead-protein complex and discussion on fabrication of Hall's Sensor. The design also shows the inductive coil on the top the Hall's sensor that is used to magnetize the beads.

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Chung DWY, Bhalla N, Li H-W, Ye YY, Yang HC, Pijanowska DG. Hall’s Effect Based Sensing Mechanism for Nano Super Paramagnetic Particle-Protein Complex Structure. 2012. Paper presented at IEEE-Asia Pacific Conference on Transducers APCOT, Nanjing, China. https://doi.org/10.13140/2.1.3415.7449