Information on the status of long-chain polyunsaturated fatty acids (LCPUFAs) in pregnancy and breast milk in very high fish-eating populations is limited. The aim of this study was to examine dietary intake and changes in fatty acid status in a population of pregnant women in the Republic of Seychelles. Serum docosahexaenoic acid (DHA) decreased significantly between 28-week gestation and delivery (n = 196). DHA status did not correlate significantly with length of gestation and was not associated with self-reported fish intake, which was high at 527 g/week. In breast milk, the ratio of DHA to arachidonic acid (AA) was consistent with those observed in other high fish-eating populations. Overall the data suggest that high exposure to LCPUFAs from habitual fish consumption does not prevent the documented decrease in LCPUFA status in pregnancy that occurs as a result of foetal accretion in the third trimester of pregnancy. (C) 2008 Elsevier Ltd. All rights reserved.
|Journal||Prostaglandins, Leukotrienes and Essential Fatty Acids|
|Publication status||Published - Jun 2008|
Bonham, M. P., Duffy, E. M., Wallace, J., Robson, P. J., Myers, G. J., Davidson, P. W., Clarkson, T. W., Shamlaye, C. F., & Strain, JJ. (2008). Habitual fish consumption does not prevent a decrease in LCPUFA status in pregnant women (the Seychelles Child Development Nutrition Study). Prostaglandins, Leukotrienes and Essential Fatty Acids, 78(6), 343-350. https://doi.org/10.1016/j.plefa.2008.04.005