GIP renaissance

Research output: Contribution to journalArticle

Abstract

A cynical commentator might observe that the progression of regulatory peptide research generally conforms to the following scenario. An enterprising chemist/ biochemist/molecular biologist either purifies and characterizes a previously undescribed biologically active peptide or infers its existence from the nucleotide sequence of a gene or cDNA. This is quickly followed by a burst of intense activity in several laboratories to define its role in physiology and pathophysiology (the “bandwagon” effect) resulting in far-reaching claims for the peptide’s importance in terms of clinical relevance. When these often exaggerated claims are found not to be justified, interest in the peptide declines precipitously.
Original languageEnglish
Article number170266
JournalPeptides
Volume125
Publication statusAccepted/In press - 23 Jan 2020

Keywords

  • GIP

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  • Cite this

    Flatt, PR., & Conlon, JM. (Accepted/In press). GIP renaissance. Peptides, 125, [170266].