Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

Y. Lu, V. Vitart, K.P. Burdon, C.C. Khor, Y. Bykhovskaya, A. Mirshahi, A.W. Hewitt, D. Koehn, P.G. Hysi, W.D. Ramdas, T. Zeller, E.N. Vithana, B.K. Cornes, W.-T. Tay, E.S. Tai, C.-Y. Cheng, J. Liu, J.-N. Foo, S.M. Saw, G. Thorleifsson & 70 others K. Stefansson, D.P. Dimasi, R.A. Mills, J. Mountain, W. Ang, R. Hoehn, V.J.M. Verhoeven, F. Grus, R. Wolfs, R. Castagne, K.J. Lackner, H. Springelkamp, J. Yang, F. Jonasson, D.Y.L. Leung, L.J. Chen, C.C.Y. Tham, I. Rudan, Z. Vatavuk, C. Hayward, J. Gibson, A.J. Cree, A. MacLeod, S. Ennis, O. Polasek, H. Campbell, J.F. Wilson, A.C. Viswanathan, B. Fleck, X. Li, D. Siscovick, K.D. Taylor, J.I. Rotter, S. Yazar, M. Ulmer, J. Li, B.L. Yaspan, A.B. Ozel, J.E. Richards, S.E. Moroi, J.L. Haines, J.H. Kang, L.R. Pasquale, R.R. Allingham, A. Ashley-Koch, P. Mitchell, J.J. Wang, A.F. Wright, C. Pennell, T.D. Spector, T.L. Young, C.C.W. Klaver, N.G. Martin, G.W. Montgomery, M.G. Anderson, T. Aung, C.E. Willoughby, J.L. Wiggs, C.P. Pang, U. Thorsteinsdottir, A.J. Lotery, C.J. Hammond, C.M. Van Duijn, M.A. Hauser, Y.S. Rabinowitz, N. Pfeiffer, D.A. MacKey, J.E. Craig, S. MacGregor, T.Y. Wong

Research output: Contribution to journalArticle

141 Citations (Scopus)
LanguageEnglish
Pages155-163
Number of pages9
JournalNature Genetics
Volume45
Issue number2
DOIs
Publication statusPublished - 6 Jan 2013

Cite this

Lu, Y., Vitart, V., Burdon, K. P., Khor, C. C., Bykhovskaya, Y., Mirshahi, A., ... Wong, T. Y. (2013). Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. Nature Genetics, 45(2), 155-163. https://doi.org/10.1038/ng.2506
Lu, Y. ; Vitart, V. ; Burdon, K.P. ; Khor, C.C. ; Bykhovskaya, Y. ; Mirshahi, A. ; Hewitt, A.W. ; Koehn, D. ; Hysi, P.G. ; Ramdas, W.D. ; Zeller, T. ; Vithana, E.N. ; Cornes, B.K. ; Tay, W.-T. ; Tai, E.S. ; Cheng, C.-Y. ; Liu, J. ; Foo, J.-N. ; Saw, S.M. ; Thorleifsson, G. ; Stefansson, K. ; Dimasi, D.P. ; Mills, R.A. ; Mountain, J. ; Ang, W. ; Hoehn, R. ; Verhoeven, V.J.M. ; Grus, F. ; Wolfs, R. ; Castagne, R. ; Lackner, K.J. ; Springelkamp, H. ; Yang, J. ; Jonasson, F. ; Leung, D.Y.L. ; Chen, L.J. ; Tham, C.C.Y. ; Rudan, I. ; Vatavuk, Z. ; Hayward, C. ; Gibson, J. ; Cree, A.J. ; MacLeod, A. ; Ennis, S. ; Polasek, O. ; Campbell, H. ; Wilson, J.F. ; Viswanathan, A.C. ; Fleck, B. ; Li, X. ; Siscovick, D. ; Taylor, K.D. ; Rotter, J.I. ; Yazar, S. ; Ulmer, M. ; Li, J. ; Yaspan, B.L. ; Ozel, A.B. ; Richards, J.E. ; Moroi, S.E. ; Haines, J.L. ; Kang, J.H. ; Pasquale, L.R. ; Allingham, R.R. ; Ashley-Koch, A. ; Mitchell, P. ; Wang, J.J. ; Wright, A.F. ; Pennell, C. ; Spector, T.D. ; Young, T.L. ; Klaver, C.C.W. ; Martin, N.G. ; Montgomery, G.W. ; Anderson, M.G. ; Aung, T. ; Willoughby, C.E. ; Wiggs, J.L. ; Pang, C.P. ; Thorsteinsdottir, U. ; Lotery, A.J. ; Hammond, C.J. ; Van Duijn, C.M. ; Hauser, M.A. ; Rabinowitz, Y.S. ; Pfeiffer, N. ; MacKey, D.A. ; Craig, J.E. ; MacGregor, S. ; Wong, T.Y. / Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. In: Nature Genetics. 2013 ; Vol. 45, No. 2. pp. 155-163.
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author = "Y. Lu and V. Vitart and K.P. Burdon and C.C. Khor and Y. Bykhovskaya and A. Mirshahi and A.W. Hewitt and D. Koehn and P.G. Hysi and W.D. Ramdas and T. Zeller and E.N. Vithana and B.K. Cornes and W.-T. Tay and E.S. Tai and C.-Y. Cheng and J. Liu and J.-N. Foo and S.M. Saw and G. Thorleifsson and K. Stefansson and D.P. Dimasi and R.A. Mills and J. Mountain and W. Ang and R. Hoehn and V.J.M. Verhoeven and F. Grus and R. Wolfs and R. Castagne and K.J. Lackner and H. Springelkamp and J. Yang and F. Jonasson and D.Y.L. Leung and L.J. Chen and C.C.Y. Tham and I. Rudan and Z. Vatavuk and C. Hayward and J. Gibson and A.J. Cree and A. MacLeod and S. Ennis and O. Polasek and H. Campbell and J.F. Wilson and A.C. Viswanathan and B. Fleck and X. Li and D. Siscovick and K.D. Taylor and J.I. Rotter and S. Yazar and M. Ulmer and J. Li and B.L. Yaspan and A.B. Ozel and J.E. Richards and S.E. Moroi and J.L. Haines and J.H. Kang and L.R. Pasquale and R.R. Allingham and A. Ashley-Koch and P. Mitchell and J.J. Wang and A.F. Wright and C. Pennell and T.D. Spector and T.L. Young and C.C.W. Klaver and N.G. Martin and G.W. Montgomery and M.G. Anderson and T. Aung and C.E. Willoughby and J.L. Wiggs and C.P. Pang and U. Thorsteinsdottir and A.J. Lotery and C.J. Hammond and {Van Duijn}, C.M. and M.A. Hauser and Y.S. Rabinowitz and N. Pfeiffer and D.A. MacKey and J.E. Craig and S. MacGregor and T.Y. Wong",
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Lu, Y, Vitart, V, Burdon, KP, Khor, CC, Bykhovskaya, Y, Mirshahi, A, Hewitt, AW, Koehn, D, Hysi, PG, Ramdas, WD, Zeller, T, Vithana, EN, Cornes, BK, Tay, W-T, Tai, ES, Cheng, C-Y, Liu, J, Foo, J-N, Saw, SM, Thorleifsson, G, Stefansson, K, Dimasi, DP, Mills, RA, Mountain, J, Ang, W, Hoehn, R, Verhoeven, VJM, Grus, F, Wolfs, R, Castagne, R, Lackner, KJ, Springelkamp, H, Yang, J, Jonasson, F, Leung, DYL, Chen, LJ, Tham, CCY, Rudan, I, Vatavuk, Z, Hayward, C, Gibson, J, Cree, AJ, MacLeod, A, Ennis, S, Polasek, O, Campbell, H, Wilson, JF, Viswanathan, AC, Fleck, B, Li, X, Siscovick, D, Taylor, KD, Rotter, JI, Yazar, S, Ulmer, M, Li, J, Yaspan, BL, Ozel, AB, Richards, JE, Moroi, SE, Haines, JL, Kang, JH, Pasquale, LR, Allingham, RR, Ashley-Koch, A, Mitchell, P, Wang, JJ, Wright, AF, Pennell, C, Spector, TD, Young, TL, Klaver, CCW, Martin, NG, Montgomery, GW, Anderson, MG, Aung, T, Willoughby, CE, Wiggs, JL, Pang, CP, Thorsteinsdottir, U, Lotery, AJ, Hammond, CJ, Van Duijn, CM, Hauser, MA, Rabinowitz, YS, Pfeiffer, N, MacKey, DA, Craig, JE, MacGregor, S & Wong, TY 2013, 'Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus', Nature Genetics, vol. 45, no. 2, pp. 155-163. https://doi.org/10.1038/ng.2506

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. / Lu, Y.; Vitart, V.; Burdon, K.P.; Khor, C.C.; Bykhovskaya, Y.; Mirshahi, A.; Hewitt, A.W.; Koehn, D.; Hysi, P.G.; Ramdas, W.D.; Zeller, T.; Vithana, E.N.; Cornes, B.K.; Tay, W.-T.; Tai, E.S.; Cheng, C.-Y.; Liu, J.; Foo, J.-N.; Saw, S.M.; Thorleifsson, G.; Stefansson, K.; Dimasi, D.P.; Mills, R.A.; Mountain, J.; Ang, W.; Hoehn, R.; Verhoeven, V.J.M.; Grus, F.; Wolfs, R.; Castagne, R.; Lackner, K.J.; Springelkamp, H.; Yang, J.; Jonasson, F.; Leung, D.Y.L.; Chen, L.J.; Tham, C.C.Y.; Rudan, I.; Vatavuk, Z.; Hayward, C.; Gibson, J.; Cree, A.J.; MacLeod, A.; Ennis, S.; Polasek, O.; Campbell, H.; Wilson, J.F.; Viswanathan, A.C.; Fleck, B.; Li, X.; Siscovick, D.; Taylor, K.D.; Rotter, J.I.; Yazar, S.; Ulmer, M.; Li, J.; Yaspan, B.L.; Ozel, A.B.; Richards, J.E.; Moroi, S.E.; Haines, J.L.; Kang, J.H.; Pasquale, L.R.; Allingham, R.R.; Ashley-Koch, A.; Mitchell, P.; Wang, J.J.; Wright, A.F.; Pennell, C.; Spector, T.D.; Young, T.L.; Klaver, C.C.W.; Martin, N.G.; Montgomery, G.W.; Anderson, M.G.; Aung, T.; Willoughby, C.E.; Wiggs, J.L.; Pang, C.P.; Thorsteinsdottir, U.; Lotery, A.J.; Hammond, C.J.; Van Duijn, C.M.; Hauser, M.A.; Rabinowitz, Y.S.; Pfeiffer, N.; MacKey, D.A.; Craig, J.E.; MacGregor, S.; Wong, T.Y.

In: Nature Genetics, Vol. 45, No. 2, 06.01.2013, p. 155-163.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

AU - Lu, Y.

AU - Vitart, V.

AU - Burdon, K.P.

AU - Khor, C.C.

AU - Bykhovskaya, Y.

AU - Mirshahi, A.

AU - Hewitt, A.W.

AU - Koehn, D.

AU - Hysi, P.G.

AU - Ramdas, W.D.

AU - Zeller, T.

AU - Vithana, E.N.

AU - Cornes, B.K.

AU - Tay, W.-T.

AU - Tai, E.S.

AU - Cheng, C.-Y.

AU - Liu, J.

AU - Foo, J.-N.

AU - Saw, S.M.

AU - Thorleifsson, G.

AU - Stefansson, K.

AU - Dimasi, D.P.

AU - Mills, R.A.

AU - Mountain, J.

AU - Ang, W.

AU - Hoehn, R.

AU - Verhoeven, V.J.M.

AU - Grus, F.

AU - Wolfs, R.

AU - Castagne, R.

AU - Lackner, K.J.

AU - Springelkamp, H.

AU - Yang, J.

AU - Jonasson, F.

AU - Leung, D.Y.L.

AU - Chen, L.J.

AU - Tham, C.C.Y.

AU - Rudan, I.

AU - Vatavuk, Z.

AU - Hayward, C.

AU - Gibson, J.

AU - Cree, A.J.

AU - MacLeod, A.

AU - Ennis, S.

AU - Polasek, O.

AU - Campbell, H.

AU - Wilson, J.F.

AU - Viswanathan, A.C.

AU - Fleck, B.

AU - Li, X.

AU - Siscovick, D.

AU - Taylor, K.D.

AU - Rotter, J.I.

AU - Yazar, S.

AU - Ulmer, M.

AU - Li, J.

AU - Yaspan, B.L.

AU - Ozel, A.B.

AU - Richards, J.E.

AU - Moroi, S.E.

AU - Haines, J.L.

AU - Kang, J.H.

AU - Pasquale, L.R.

AU - Allingham, R.R.

AU - Ashley-Koch, A.

AU - Mitchell, P.

AU - Wang, J.J.

AU - Wright, A.F.

AU - Pennell, C.

AU - Spector, T.D.

AU - Young, T.L.

AU - Klaver, C.C.W.

AU - Martin, N.G.

AU - Montgomery, G.W.

AU - Anderson, M.G.

AU - Aung, T.

AU - Willoughby, C.E.

AU - Wiggs, J.L.

AU - Pang, C.P.

AU - Thorsteinsdottir, U.

AU - Lotery, A.J.

AU - Hammond, C.J.

AU - Van Duijn, C.M.

AU - Hauser, M.A.

AU - Rabinowitz, Y.S.

AU - Pfeiffer, N.

AU - MacKey, D.A.

AU - Craig, J.E.

AU - MacGregor, S.

AU - Wong, T.Y.

N1 - Cited By :118 Export Date: 6 September 2018

PY - 2013/1/6

Y1 - 2013/1/6

U2 - 10.1038/ng.2506

DO - 10.1038/ng.2506

M3 - Article

VL - 45

SP - 155

EP - 163

JO - Nature Genetics

T2 - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

IS - 2

ER -