Abstract
This study investigates the effects of gastric inhibitory polypeptide (GIP) and glycated GIP (glucitol adduct of GIP) on glucose uptake and metabolism in muscle. Glycated GIP (molecular mass 5147.2 Da) was purified by HPLC following in vitro incubation under hyperglycaemic reducing conditions (24 h at pH 7.4). GIP (10(-10)-10(-8) mol/l) significantly stimulated (1.4- to 1.5-fold, P
| Original language | English |
|---|---|
| Pages (from-to) | 237-243 |
| Journal | Journal of Endrocrinology |
| Volume | 156 |
| Issue number | 2 |
| Publication status | Published (in print/issue) - Feb 1998 |