Further evidence for heredity of pterygium

Vito Romano, Bernhard Steger, Adriana Kovacova, Stephen B. Kaye, Colin Willoughby

    Research output: Contribution to journalArticle

    4 Citations (Scopus)

    Abstract

    Epidemiological reports strongly indicate that pterygium is an ophthalmoheliosis: a sun-related eye disease. Familial occurrence of pterygium is rare but supports the concept that heredity may predispose the conjunctiva to react abnormally to atmospheric-environmental stimuli. We describe a two generation Caucasian family of five members from the United Kingdom, four of whom developed pterygia in early adulthood with autosomal dominant inheritance. The present report confirms the significance of heredity in the pathogenesis of pterygium. Understanding the genetic basis of pterygium pathogenesis is clinically relevant, particularly in the management of patients who develop recurrent and aggressive pterygia at younger ages.
    LanguageEnglish
    Pages434-436
    JournalOphthalmic Genetics
    Volume37
    Issue number4
    DOIs
    Publication statusAccepted/In press - 10 Oct 2015

    Fingerprint

    Pterygium
    Heredity
    Eye Diseases
    Conjunctiva
    Solar System

    Keywords

    • Familial pterygium
    • heredity
    • inheritance
    • pterygium

    Cite this

    Romano, V., Steger, B., Kovacova, A., Kaye, S. B., & Willoughby, C. (Accepted/In press). Further evidence for heredity of pterygium. Ophthalmic Genetics, 37(4), 434-436. https://doi.org/10.3109/13816810.2015.1111911
    Romano, Vito ; Steger, Bernhard ; Kovacova, Adriana ; Kaye, Stephen B. ; Willoughby, Colin. / Further evidence for heredity of pterygium. In: Ophthalmic Genetics. 2015 ; Vol. 37, No. 4. pp. 434-436.
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    Romano, V, Steger, B, Kovacova, A, Kaye, SB & Willoughby, C 2015, 'Further evidence for heredity of pterygium', Ophthalmic Genetics, vol. 37, no. 4, pp. 434-436. https://doi.org/10.3109/13816810.2015.1111911

    Further evidence for heredity of pterygium. / Romano, Vito; Steger, Bernhard; Kovacova, Adriana; Kaye, Stephen B.; Willoughby, Colin.

    In: Ophthalmic Genetics, Vol. 37, No. 4, 10.10.2015, p. 434-436.

    Research output: Contribution to journalArticle

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    AU - Romano, Vito

    AU - Steger, Bernhard

    AU - Kovacova, Adriana

    AU - Kaye, Stephen B.

    AU - Willoughby, Colin

    PY - 2015/10/10

    Y1 - 2015/10/10

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    AB - Epidemiological reports strongly indicate that pterygium is an ophthalmoheliosis: a sun-related eye disease. Familial occurrence of pterygium is rare but supports the concept that heredity may predispose the conjunctiva to react abnormally to atmospheric-environmental stimuli. We describe a two generation Caucasian family of five members from the United Kingdom, four of whom developed pterygia in early adulthood with autosomal dominant inheritance. The present report confirms the significance of heredity in the pathogenesis of pterygium. Understanding the genetic basis of pterygium pathogenesis is clinically relevant, particularly in the management of patients who develop recurrent and aggressive pterygia at younger ages.

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    KW - heredity

    KW - inheritance

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