Further evidence for heredity of pterygium

Vito Romano, Bernhard Steger, Adriana Kovacova, Stephen B. Kaye, Colin Willoughby

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    11 Citations (Scopus)


    Epidemiological reports strongly indicate that pterygium is an ophthalmoheliosis: a sun-related eye disease. Familial occurrence of pterygium is rare but supports the concept that heredity may predispose the conjunctiva to react abnormally to atmospheric-environmental stimuli. We describe a two generation Caucasian family of five members from the United Kingdom, four of whom developed pterygia in early adulthood with autosomal dominant inheritance. The present report confirms the significance of heredity in the pathogenesis of pterygium. Understanding the genetic basis of pterygium pathogenesis is clinically relevant, particularly in the management of patients who develop recurrent and aggressive pterygia at younger ages.
    Original languageEnglish
    Pages (from-to)434-436
    JournalOphthalmic Genetics
    Issue number4
    Publication statusAccepted/In press - 10 Oct 2015


    • Familial pterygium
    • heredity
    • inheritance
    • pterygium


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