Formulation Development of DS003 in Ethylene Vinyl Acetate Vaginal Rings

Matthew Wilson; K Malcolm; Wendy Blanda; Jeremy Nutgall; Anita Garg; Andrew Brimer; P Boyd

doi:10.1089/aid.2016.5000.abstracts

Formulation Development of DS003 in Ethylene Vinyl Acetate Vaginal Rings

Matthew Wilson
, K Malcolm
, Wendy Blanda
, Jeremy Nutgall
, Anita Garg
, Andrew Brimer
, P Boyd

Research output: Contribution to conference › Abstract

Abstract

DS003 is a potent antiretroviral entry inhibitor molecule being developed by the International Partnership for Microbicides (IPM) as a vaginal microbicide candidate. With the ultimate goal of developing a combination microbicide vaginal ring containing DS003 and dapivirine, this study evaluated the potential for incorporation of high loadings of DS003 in ethylene vinyl acetate (EVA) matrix-type rings suitable for testing in macaques.

Original language	English
Pages	P07.39
DOIs	https://doi.org/10.1089/aid.2016.5000.abstracts
Publication status	Published (in print/issue) - 1 Oct 2016
Event	2nd HIV Research for Prevention Conference - Chicago, United States Duration: 17 Oct 2016 → 21 Oct 2016

Conference

Conference	2nd HIV Research for Prevention Conference
Abbreviated title	HIVR4P
Country/Territory	United States
City	Chicago
Period	17/10/16 → 21/10/16

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10.1089/aid.2016.5000.abstracts

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title = "Formulation Development of DS003 in Ethylene Vinyl Acetate Vaginal Rings",

abstract = "DS003 is a potent antiretroviral entry inhibitor molecule being developed by the International Partnership for Microbicides (IPM) as a vaginal microbicide candidate. With the ultimate goal of developing a combination microbicide vaginal ring containing DS003 and dapivirine, this study evaluated the potential for incorporation of high loadings of DS003 in ethylene vinyl acetate (EVA) matrix-type rings suitable for testing in macaques.",

author = "Matthew Wilson and K Malcolm and Wendy Blanda and Jeremy Nutgall and Anita Garg and Andrew Brimer and P Boyd",

year = "2016",

month = oct,

day = "1",

doi = "10.1089/aid.2016.5000.abstracts",

language = "English",

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note = "2nd HIV Research for Prevention Conference , HIVR4P ; Conference date: 17-10-2016 Through 21-10-2016",

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T1 - Formulation Development of DS003 in Ethylene Vinyl Acetate Vaginal Rings

AU - Wilson, Matthew

AU - Malcolm, K

AU - Blanda, Wendy

AU - Nutgall, Jeremy

AU - Garg, Anita

AU - Brimer, Andrew

AU - Boyd, P

PY - 2016/10/1

Y1 - 2016/10/1

N2 - DS003 is a potent antiretroviral entry inhibitor molecule being developed by the International Partnership for Microbicides (IPM) as a vaginal microbicide candidate. With the ultimate goal of developing a combination microbicide vaginal ring containing DS003 and dapivirine, this study evaluated the potential for incorporation of high loadings of DS003 in ethylene vinyl acetate (EVA) matrix-type rings suitable for testing in macaques.

AB - DS003 is a potent antiretroviral entry inhibitor molecule being developed by the International Partnership for Microbicides (IPM) as a vaginal microbicide candidate. With the ultimate goal of developing a combination microbicide vaginal ring containing DS003 and dapivirine, this study evaluated the potential for incorporation of high loadings of DS003 in ethylene vinyl acetate (EVA) matrix-type rings suitable for testing in macaques.

U2 - 10.1089/aid.2016.5000.abstracts

DO - 10.1089/aid.2016.5000.abstracts

M3 - Abstract

SP - P07.39

T2 - 2nd HIV Research for Prevention Conference

Y2 - 17 October 2016 through 21 October 2016

ER -

Formulation Development of DS003 in Ethylene Vinyl Acetate Vaginal Rings

Abstract

Conference

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