Formulation Development of DS003 in Ethylene Vinyl Acetate Vaginal Rings

Matthew Wilson, K Malcolm, Wendy Blanda, Jeremy Nutgall, Anita Garg, Andrew Brimer, P Boyd

Research output: Contribution to conferenceAbstract

Abstract

DS003 is a potent antiretroviral entry inhibitor molecule being developed by the International Partnership for Microbicides (IPM) as a vaginal microbicide candidate. With the ultimate goal of developing a combination microbicide vaginal ring containing DS003 and dapivirine, this study evaluated the potential for incorporation of high loadings of DS003 in ethylene vinyl acetate (EVA) matrix-type rings suitable for testing in macaques.

Conference

Conference2nd HIV Research for Prevention Conference
Abbreviated titleHIVR4P
CountryUnited States
CityChicago
Period17/10/1621/10/16

Fingerprint

Female Contraceptive Devices
Anti-Infective Agents
Molecules
Testing
ethylene
vinyl acetate

Cite this

Wilson, M., Malcolm, K., Blanda, W., Nutgall, J., Garg, A., Brimer, A., & Boyd, P. (2016). Formulation Development of DS003 in Ethylene Vinyl Acetate Vaginal Rings. P07.39. Abstract from 2nd HIV Research for Prevention Conference , Chicago, United States. https://doi.org/10.1089/aid.2016.5000.abstracts
Wilson, Matthew ; Malcolm, K ; Blanda, Wendy ; Nutgall, Jeremy ; Garg, Anita ; Brimer, Andrew ; Boyd, P. / Formulation Development of DS003 in Ethylene Vinyl Acetate Vaginal Rings. Abstract from 2nd HIV Research for Prevention Conference , Chicago, United States.
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title = "Formulation Development of DS003 in Ethylene Vinyl Acetate Vaginal Rings",
abstract = "DS003 is a potent antiretroviral entry inhibitor molecule being developed by the International Partnership for Microbicides (IPM) as a vaginal microbicide candidate. With the ultimate goal of developing a combination microbicide vaginal ring containing DS003 and dapivirine, this study evaluated the potential for incorporation of high loadings of DS003 in ethylene vinyl acetate (EVA) matrix-type rings suitable for testing in macaques.",
author = "Matthew Wilson and K Malcolm and Wendy Blanda and Jeremy Nutgall and Anita Garg and Andrew Brimer and P Boyd",
year = "2016",
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doi = "10.1089/aid.2016.5000.abstracts",
language = "English",
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note = "2nd HIV Research for Prevention Conference , HIVR4P ; Conference date: 17-10-2016 Through 21-10-2016",

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Wilson, M, Malcolm, K, Blanda, W, Nutgall, J, Garg, A, Brimer, A & Boyd, P 2016, 'Formulation Development of DS003 in Ethylene Vinyl Acetate Vaginal Rings' 2nd HIV Research for Prevention Conference , Chicago, United States, 17/10/16 - 21/10/16, pp. P07.39. https://doi.org/10.1089/aid.2016.5000.abstracts

Formulation Development of DS003 in Ethylene Vinyl Acetate Vaginal Rings. / Wilson, Matthew; Malcolm, K; Blanda, Wendy; Nutgall, Jeremy; Garg, Anita; Brimer, Andrew; Boyd, P.

2016. P07.39 Abstract from 2nd HIV Research for Prevention Conference , Chicago, United States.

Research output: Contribution to conferenceAbstract

TY - CONF

T1 - Formulation Development of DS003 in Ethylene Vinyl Acetate Vaginal Rings

AU - Wilson, Matthew

AU - Malcolm, K

AU - Blanda, Wendy

AU - Nutgall, Jeremy

AU - Garg, Anita

AU - Brimer, Andrew

AU - Boyd, P

PY - 2016/10/1

Y1 - 2016/10/1

N2 - DS003 is a potent antiretroviral entry inhibitor molecule being developed by the International Partnership for Microbicides (IPM) as a vaginal microbicide candidate. With the ultimate goal of developing a combination microbicide vaginal ring containing DS003 and dapivirine, this study evaluated the potential for incorporation of high loadings of DS003 in ethylene vinyl acetate (EVA) matrix-type rings suitable for testing in macaques.

AB - DS003 is a potent antiretroviral entry inhibitor molecule being developed by the International Partnership for Microbicides (IPM) as a vaginal microbicide candidate. With the ultimate goal of developing a combination microbicide vaginal ring containing DS003 and dapivirine, this study evaluated the potential for incorporation of high loadings of DS003 in ethylene vinyl acetate (EVA) matrix-type rings suitable for testing in macaques.

U2 - 10.1089/aid.2016.5000.abstracts

DO - 10.1089/aid.2016.5000.abstracts

M3 - Abstract

SP - P07.39

ER -

Wilson M, Malcolm K, Blanda W, Nutgall J, Garg A, Brimer A et al. Formulation Development of DS003 in Ethylene Vinyl Acetate Vaginal Rings. 2016. Abstract from 2nd HIV Research for Prevention Conference , Chicago, United States. https://doi.org/10.1089/aid.2016.5000.abstracts