Episodic memory and learning in patients with chronic schizophrenia.

T M Rushe, P W Woodruff, R M Murray, R G Morris

    Research output: Contribution to journalArticle

    90 Citations (Scopus)

    Abstract

    This study explored the pattern of memory functioning in 58 patients with chronic schizophrenia and compared their performance with 53 normal controls. Multiple domains of memory were assessed, including verbal and non-verbal memory span, verbal and non-verbal paired associate learning, verbal and visual long-term memory, spatial and non-spatial conditional associative learning, recognition memory and memory for temporal order. Consistent with previous studies, substantial deficits in long-term memory were observed, with relative preservation of memory span. Memory for temporal order and recognition memory was intact, although significant deficits were observed on the conditional associative learning tasks. There was no evidence of lateralized memory impairment. In these respects, the pattern of memory impairment in schizophrenia is more similar in nature to that found in patients with memory dysfunction following mesiotemporal lobe lesions, rather than that associated with focal frontal lobe damage.
    LanguageEnglish
    Pages85-96
    JournalSchizophrenia Research
    Volume35
    Issue number1
    Publication statusPublished - 1999

    Fingerprint

    Episodic Memory
    Schizophrenia
    Learning
    Long-Term Memory
    Paired-Associate Learning
    Frontal Lobe

    Cite this

    Rushe, T. M., Woodruff, P. W., Murray, R. M., & Morris, R. G. (1999). Episodic memory and learning in patients with chronic schizophrenia. 35(1), 85-96.
    Rushe, T M ; Woodruff, P W ; Murray, R M ; Morris, R G. / Episodic memory and learning in patients with chronic schizophrenia. 1999 ; Vol. 35, No. 1. pp. 85-96.
    @article{913b170b241942cfa43799423c8b99f6,
    title = "Episodic memory and learning in patients with chronic schizophrenia.",
    abstract = "This study explored the pattern of memory functioning in 58 patients with chronic schizophrenia and compared their performance with 53 normal controls. Multiple domains of memory were assessed, including verbal and non-verbal memory span, verbal and non-verbal paired associate learning, verbal and visual long-term memory, spatial and non-spatial conditional associative learning, recognition memory and memory for temporal order. Consistent with previous studies, substantial deficits in long-term memory were observed, with relative preservation of memory span. Memory for temporal order and recognition memory was intact, although significant deficits were observed on the conditional associative learning tasks. There was no evidence of lateralized memory impairment. In these respects, the pattern of memory impairment in schizophrenia is more similar in nature to that found in patients with memory dysfunction following mesiotemporal lobe lesions, rather than that associated with focal frontal lobe damage.",
    author = "Rushe, {T M} and Woodruff, {P W} and Murray, {R M} and Morris, {R G}",
    year = "1999",
    language = "English",
    volume = "35",
    pages = "85--96",
    number = "1",

    }

    Rushe, TM, Woodruff, PW, Murray, RM & Morris, RG 1999, 'Episodic memory and learning in patients with chronic schizophrenia.', vol. 35, no. 1, pp. 85-96.

    Episodic memory and learning in patients with chronic schizophrenia. / Rushe, T M; Woodruff, P W; Murray, R M; Morris, R G.

    Vol. 35, No. 1, 1999, p. 85-96.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Episodic memory and learning in patients with chronic schizophrenia.

    AU - Rushe, T M

    AU - Woodruff, P W

    AU - Murray, R M

    AU - Morris, R G

    PY - 1999

    Y1 - 1999

    N2 - This study explored the pattern of memory functioning in 58 patients with chronic schizophrenia and compared their performance with 53 normal controls. Multiple domains of memory were assessed, including verbal and non-verbal memory span, verbal and non-verbal paired associate learning, verbal and visual long-term memory, spatial and non-spatial conditional associative learning, recognition memory and memory for temporal order. Consistent with previous studies, substantial deficits in long-term memory were observed, with relative preservation of memory span. Memory for temporal order and recognition memory was intact, although significant deficits were observed on the conditional associative learning tasks. There was no evidence of lateralized memory impairment. In these respects, the pattern of memory impairment in schizophrenia is more similar in nature to that found in patients with memory dysfunction following mesiotemporal lobe lesions, rather than that associated with focal frontal lobe damage.

    AB - This study explored the pattern of memory functioning in 58 patients with chronic schizophrenia and compared their performance with 53 normal controls. Multiple domains of memory were assessed, including verbal and non-verbal memory span, verbal and non-verbal paired associate learning, verbal and visual long-term memory, spatial and non-spatial conditional associative learning, recognition memory and memory for temporal order. Consistent with previous studies, substantial deficits in long-term memory were observed, with relative preservation of memory span. Memory for temporal order and recognition memory was intact, although significant deficits were observed on the conditional associative learning tasks. There was no evidence of lateralized memory impairment. In these respects, the pattern of memory impairment in schizophrenia is more similar in nature to that found in patients with memory dysfunction following mesiotemporal lobe lesions, rather than that associated with focal frontal lobe damage.

    M3 - Article

    VL - 35

    SP - 85

    EP - 96

    IS - 1

    ER -

    Rushe TM, Woodruff PW, Murray RM, Morris RG. Episodic memory and learning in patients with chronic schizophrenia. 1999;35(1):85-96.