Enhanced ROS production and cell death through combined photo- and sono-activation of conventional photosensitising drugs.

Bridgeen McCaughan, C Rouanet, Colin Fowley, N Nomikou, Anthony McHale, John Callan

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

A combination of light and ultrasound activation of two conventional photosensitising drugs, methylene blue and rose bengal, was shown to generate higher levels of reactive oxygen species (ROS) and lower LD50 values than either light or ultrasound activation alone.
Original languageEnglish
Pages (from-to)5750-5752
JournalBioorganic and Medicinal Chemistry Letters
Volume21
Issue number19
DOIs
Publication statusPublished - 1 Oct 2011

Fingerprint Dive into the research topics of 'Enhanced ROS production and cell death through combined photo- and sono-activation of conventional photosensitising drugs.'. Together they form a unique fingerprint.

Cite this