Emblica officinalis stimulates the secretion and action of insulin and inhibits starch digestion and protein glycation in vitro

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Abstract

Aim: Medicinal, edible and aromatic plants and natural products have been used worldwide for the management of diabetes mellitus. The aim of this study was to investigate the efficacy and mode of action of Emblica officinalis Gaertn. (Phyllanthaceae) used traditionally for treatment of diabetes. Study Design: Using multiple In vitro models; this study was designed to investigate the antidiabetes efficacy and mode of action of E. officinalis.Place and Duration of Study: School of Biomedical Sciences, University of Ulster, 2001-2004Results: E. officinalis aqueous extracts (AEs) stimulated basal insulin output and potentiated glucose-stimulated insulin secretion concentration-dependently in the clonal pancreatic beta cell line, BRIN-BD11 (p
LanguageEnglish
Pages753-770
JournalEuropean Journal of Medicinal Plants
Volume4
Issue number6
DOIs
Publication statusPublished - 20 Mar 2014

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Phyllanthus emblica
Starch
Proteolysis
Insulin
Edible Plants
Insulin-Secreting Cells
Biological Products
Diabetes Mellitus
Glucose
Cell Line
In Vitro Techniques

Keywords

  • Emblica officinalis Gaertn
  • (Phyllanthaceae)
  • insulin secretion
  • insulin action
  • starch digestion
  • peptide glycation.

Cite this

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abstract = "Aim: Medicinal, edible and aromatic plants and natural products have been used worldwide for the management of diabetes mellitus. The aim of this study was to investigate the efficacy and mode of action of Emblica officinalis Gaertn. (Phyllanthaceae) used traditionally for treatment of diabetes. Study Design: Using multiple In vitro models; this study was designed to investigate the antidiabetes efficacy and mode of action of E. officinalis.Place and Duration of Study: School of Biomedical Sciences, University of Ulster, 2001-2004Results: E. officinalis aqueous extracts (AEs) stimulated basal insulin output and potentiated glucose-stimulated insulin secretion concentration-dependently in the clonal pancreatic beta cell line, BRIN-BD11 (p",
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AU - Flatt, Peter

AU - Abdel-Wahab, YHA

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AB - Aim: Medicinal, edible and aromatic plants and natural products have been used worldwide for the management of diabetes mellitus. The aim of this study was to investigate the efficacy and mode of action of Emblica officinalis Gaertn. (Phyllanthaceae) used traditionally for treatment of diabetes. Study Design: Using multiple In vitro models; this study was designed to investigate the antidiabetes efficacy and mode of action of E. officinalis.Place and Duration of Study: School of Biomedical Sciences, University of Ulster, 2001-2004Results: E. officinalis aqueous extracts (AEs) stimulated basal insulin output and potentiated glucose-stimulated insulin secretion concentration-dependently in the clonal pancreatic beta cell line, BRIN-BD11 (p

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KW - starch digestion

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