Abstract
A review of recent applications of HPLC-electrospray ionisation mass spectrometry (ESI-MS) to the analysis of selected drugs and their metabolites is presented. The drugs are chosen according to selected structural classes in which the molecules give ESI signals as [M+1](+), [M-1](-), [M+Na](+) ions. Details are given on the fragmentations that these ionic species exhibit in-source, in ion-traps and in triple quadrupoles. The review is principally concerned with the electrospray ionisation mass spectrometric behaviour of these drugs and their metabolites but details are given of corresponding SPE and HPLC procedures. (C)2002 Elsevier Science B.V. All rights reserved.
| Original language | English |
|---|---|
| Pages (from-to) | 1-16 |
| Journal | Analytica Chimica Acta |
| Volume | 492 |
| Issue number | 1-2 |
| Publication status | Published - Sep 2003 |
Fingerprint Dive into the research topics of 'Electrospray ionisation mass spectrometric behaviour of selected drugs and their metabolites'. Together they form a unique fingerprint.
Cite this
Smyth, F. (2003). Electrospray ionisation mass spectrometric behaviour of selected drugs and their metabolites. Analytica Chimica Acta, 492(1-2), 1-16.