Cellulose acetate phthalate films are widely used as controlled release enteric coatings within the pharmaceutical industries but their properties have hitherto been unexplored within electrochemical devices. A novel approach employing controlled electrolysis has been investigated to develop a means through which the protective films can be compromised thereby enabling the release of candidate drugs. The generation of bubbles and local pH manipulation are considered and the former shown to enable rapid removal of the film and initiate reagent release.
|Early online date||14 Aug 2015|
|Publication status||Published (in print/issue) - 1 Nov 2015|
- Drug release